Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2024 May;170(5):001436.
doi: 10.1099/mic.0.001436.

Comment on the effectiveness of sodium hypochlorite against Clostridioides difficile spores

Jennifer L Cadnum  1 , Claire E Kaple  2 , William A Rutala  3 , Curtis J Donskey  4   5
Affiliations
Comment

Comment on the effectiveness of sodium hypochlorite against Clostridioides difficile spores

Jennifer L Cadnum et al. Microbiology (Reading). 2024 May.
No abstract available

Keywords: Clostridioides difficile; disinfectant; environment; sodium hypochlorite.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.. Mean (SE) log10 recovery of spores of Clostridioides difficile American Type Culture Collection (ATCC) 43598, VA 17 (a clinical ribotype 027 isolate), and R20291 (ribotype 027) after exposure times of 10 min (a), 5 min (b), and 1 min (c) using a standard quantitative disc carrier test method. Error bars represent standard error.
See this image and copyright information in PMC

References

    1. Leggett MJ, Setlow P, Sattar SA, Maillard JY. Assessing the activity of microbicides against bacterial spores: knowledge and pitfalls. J Appl Microbiol. 2016;120:1174–1180. doi: 10.1111/jam.13061. - DOI - PubMed
    1. List K: antimicrobial products registered with EPA for claims against clostridium difficile spores. [7-December-2023]. https://www.epa.gov/pesticide-registration/list-k-antimicrobial-products... n.d. accessed.
    1. Ahmed H, Joshi LT. Clostridioides difficile spores tolerate disinfection with sodium hypochlorite disinfectant and remain viable within surgical scrubs and gown fabrics. Microbiology. 2023;169:001418. doi: 10.1099/mic.0.001418. - DOI - PMC - PubMed
    1. Malyshev D, Jones IA, McKracken M, Öberg R, Harper GM, et al. Hypervirulent R20291 Clostridioides difficile spores show disinfection resilience to sodium hypochlorite despite structural changes. BMC Microbiol. 2023;23:59. doi: 10.1186/s12866-023-02787-z. - DOI - PMC - PubMed
    1. Joshi LT, Welsch A, Hawkins J, Baillie L. The effect of hospital biocide sodium dichloroisocyanurate on the viability and properties of Clostridium difficile spores. Lett Appl Microbiol. 2017;65:199–205. doi: 10.1111/lam.12768. - DOI - PubMed

MeSH terms

LinkOut - more resources