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Case Reports
. 2024 May 4:53:101408.
doi: 10.1016/j.gore.2024.101408. eCollection 2024 Jun.

HPV-independent cervical cancer associated with non-reducible pelvic organ prolapse: A case report

Sarah J Davidson  1 , Dina El-Rayes  2 , Mahmoud Khalifa  2 , Cynthia S Fok  3 , Britt K Erickson  4
Affiliations
Case Reports

HPV-independent cervical cancer associated with non-reducible pelvic organ prolapse: A case report

Sarah J Davidson et al. Gynecol Oncol Rep. .

Abstract

•The presence of concomitant non-reducible prolapse and cervical cancer is rare.•Treatment of cervical cancer complicated by non-reducible prolapse must be individualized.•The role prolapse may play in the development of HPV-negative cervical cancer is unclear.

Keywords: Cervical cancer; Human papillomavirus; Pelvic organ prolapse; Procidentia.

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Conflict of interest statement

The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: [Britt Erickson is a member of the editorial board for Gynecologic Oncology Reports, but was not involved in the editorial review or the decision to publish this article. Britt Erickson is also on the advisory board to GSK, AstraZeneca, and Merck. These companies had no involvement in the development of this manuscript. The authors have no other conflicts of interest to disclose].

Figures

Fig. 1
Fig. 1
A) Computed tomography scan at the time of diagnosis with procidentia and cervical mass present (blue arrow) and B) positron emission tomography demonstrating fludeoxyglucose-18 avidity of the cervical mass (blue arrow).
Fig. 2
Fig. 2
Non-reducible uterine prolapse with cervical mass prior to surgery. Cervical os identified by black arrow.
Fig. 3
Fig. 3
Surgical specimen including uterus (black arrow), cervix (chevron), upper vagina, and rectum (triangle).
See this image and copyright information in PMC

References

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