Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Aug 23:12:e3045.
doi: 10.31661/gmj.v12i.3045. eCollection 2023.

Postoperative Delirium and Dementia in Patients Undergoing Cardiac Surgery: A Review of Randomized Controlled Trials

Affiliations

Postoperative Delirium and Dementia in Patients Undergoing Cardiac Surgery: A Review of Randomized Controlled Trials

Venus Shahabi Raberi et al. Galen Med J. .

Abstract

Delirium and dementia are considered to be the most significant postoperative neurocognitive complications in patients undergoing cardiac surgery, particularly those aged 60 years and older, which reduces the post-surgery quality of life, prolongs hospitalization, increases costs, and elevated the rates of mortality. Nevertheless, the etiology, risk factors, and predictive biomarkers, have not been well elucidated particularly, in patients with unmanifested underline cognitive impairments. The present study aimed to review the findings on the etiology, factors increasing the risk of incidence, and predictive biomarkers of postoperative delirium and dementia after cardiac surgery, and to describe the suggested pharmacological and non-pharmacological interventions.

Keywords: Cardiac Surgery; Dementia; Postoperative Complications.

PubMed Disclaimer

Conflict of interest statement

The authors declare that there are no conflicts of interests.

References

    1. Otomo S, Maekawa K, Baba T, Goto T, Yamamoto T. Evaluation of the risk factors for neurological and neurocognitive impairment after selective cerebral perfusion in thoracic aortic surgery . Anesth. 2020;(34):527–36. - PubMed
    1. Yuhe K, Chew STH, Ang AS, Ng RRG, Boonkiangwong N, Liu W. Comparison of postoperative cognitive decline in patients undergoing conventional vs miniaturized cardiopulmonary bypass: A randomized, controlled trial . Ann Card Anaesth. 2020;3(23):309–309. - PMC - PubMed
    1. Wang P, Yin X, Chen G, Li L, Le Y, Xie Z. Perioperative probiotic treatment decreased the incidence of postoperative cognitive impairment in elderly patients following non-cardiac surgery: A randomised double-blind and placebo-controlled trial . Clin Nutr. 2021;1(40):64–71. - PubMed
    1. Wen Y. Anesthesia with propofol and sevoflurane on postoperative cognitive function of elderly patients undergoing general thoracic surgery . Pak J Pharm Sci. 2017;(30):1107–1110. - PubMed
    1. Evered L, Scott DA, Silbert B. Cognitive decline associated with anesthesia and surgery in the elderly: does this contribute to dementia prevalence . Curr Opin Psychiatry. 2017;3(30):220–6. - PubMed

LinkOut - more resources