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. 2024 May 7:15:1397338.
doi: 10.3389/fimmu.2024.1397338. eCollection 2024.

Global trends in Cryptococcus and its interactions with the host immune system: a bibliometric analysis

Shiqin Tang  1 , Ruiying Hao  1 , Xin Liu  2 , Huina He  1 , Yanan Tian  1 , Tingting Jing  3 , Zhao Liu  3 , Yanyan Xu  3 , Xiaojing Li  4
Affiliations

Global trends in Cryptococcus and its interactions with the host immune system: a bibliometric analysis

Shiqin Tang et al. Front Immunol. .

Abstract

Objectives: This manuscript undertakes a systematic examination of the research landscape concerning global Cryptococcus species and their dynamism with the host immune system spanning the past decade. It furnishes a detailed survey of leading knowledge institutions and critical focal points in this area, utilizing bibliometric analysis.

Methods: VOSviewer and CiteSpace software platforms were employed to systematically analyze and graphically depict the relevant literature indexed in the WoSCC database over the preceding ten years.

Results: In the interval between October 1, 2013, and October 1, 2023, a corpus of 795 publications was amassed. The primary research institutions involved in this study include Duke University, the University of Minnesota, and the University of Sydney. The leading trio of nations, in terms of publication volume, comprises the United States, China, and Brazil. Among the most prolific authors are Casadevall, Arturo; Wormley, Floyd L., Jr.; and Olszewski, Michal A., with the most highly cited author being Perfect, Jr. The most esteemed journal is Mbio, while Infection and Immunity commands the highest citation frequency, and the Journal of Clinical Microbiology boasts the most significant impact factor. Present research foci encompass the intricate interactions between Cryptococcus pathogenesis and host immunity, alongside immune mechanisms, complications, and immunotherapies.

Conclusion: This represents the first exhaustive scholarly review and bibliometric scrutiny of the evolving landscapes in Cryptococcus research and its interactions with the host immune system. The analyses delineated herein provide insights into prevailing research foci and trajectories, thus furnishing critical directions for subsequent inquiries in this domain.

Keywords: Cryptococcus spp.; bibliometric analysis; cryptococcosis; host immune responses; visualization techniques.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Illustrates the process of publication selection.
Figure 2
Figure 2
Depicts the annual publication output related to Cryptococcus and host immunity research from 2013 to 2023.
Figure 3
Figure 3
Visualization of the Institutions in the Field of Cryptococcus and Host Immunity Research.
Figure 4
Figure 4
Visualization of the international network of collaboration in the research field of Cryptococcus and host immunity.
Figure 5
Figure 5
Visualization of authors in Cryptococcus and host immune research from 2013 to 2023 (A). Visualization of co-cited authors in Cryptococcus and host immune research from 2013 to 2023 (B).
Figure 6
Figure 6
Visualization of Journal Publications in the Field of Research Related to Cryptococcus and Host Immune Interactions (A) and Visualization of Co-cited Journals (B).
Figure 7
Figure 7
The superimposition of two graphs representing journals related to research on Cryptococcus and host immune interactions.
Figure 8
Figure 8
Visualization (A) of co-cited references on Cryptococcus and immunology research. Cluster network diagram (B) of co-cited references.
Figure 9
Figure 9
The top 20 most frequently cited references.
Figure 10
Figure 10
Illustrates the visualization of keyword clustering (A) and keyword density (B) in the context of research on Cryptococcus and host immunity.
Figure 11
Figure 11
Depicts a timeline of keywords in the field of Cryptococcus and immune responses.
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