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Comparative Study
. 1985 Oct;26(4):254-8.
doi: 10.1111/j.1399-0039.1985.tb00968.x.

Immunoglobulins in healthy controls: HLA-B8 and sex differences

E M Cryan, F M Stevens, R Skehill, M Bourke, H Grimes, C F McCarthy
Comparative Study

Immunoglobulins in healthy controls: HLA-B8 and sex differences

E M Cryan et al. Tissue Antigens. 1985 Oct.

Abstract

Serum immunoglobulins were measured in one hundred and eighty-four healthy controls. One hundred and fifty-nine of these were also HLA typed. IgG levels did not differ with sex or HLA-B8 status. IgM levels did not differ with HLA-B8 status but were significantly higher in females than males. IgA levels were lower in females than males; they were also lower in HLA-B8 positive compared with HLA-B8 negative individuals; the lowest IgA levels were found in HLA-B8 positive females. The IgA variation may be relevant to the higher incidence of certain disorders among HLA-B8 positive individuals and among females.

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