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. 2024 May 23;13(1):11.
doi: 10.1186/s13619-024-00194-x.

New progress in roles of TGF-β signaling crosstalks in cellular functions, immunity and diseases

Shuchen Gu #  1   2   3 , Rik Derynck  4 , Ye-Guang Chen #  5   6 , Xin-Hua Feng #  7   8   9   10
Affiliations

New progress in roles of TGF-β signaling crosstalks in cellular functions, immunity and diseases

Shuchen Gu et al. Cell Regen. .

Abstract

The family of secreted dimeric proteins known as the Transforming Growth Factor-β (TGF-β) family plays a critical role in facilitating intercellular communication within multicellular animals. A recent symposium on TGF-β Biology - Signaling, Development, and Diseases, held on December 19-21, 2023, in Hangzhou, China, showcased some latest advances in our understanding TGF-β biology and also served as an important forum for scientific collaboration and exchange of ideas. More than twenty presentations and discussions at the symposium delved into the intricate mechanisms of TGF-β superfamily signaling pathways, their roles in normal development and immunity, and the pathological conditions associated with pathway dysregulation.

Keywords: Development; Diseases; Immunity; Signaling; TGF-β superfamily.

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Conflict of interest statement

Ye-Guang Chen is the Editor-in-Chief of Cell Regeneration, and Rik Derynck and Xin-Hua Feng are members of the Editorial Board for Cell Regeneration. They were not involved in the journal’s review of, or decisions related to, this manuscript.

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