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Case Reports
. 2024 Aug;17(4):593-597.
doi: 10.1007/s12328-024-01978-z. Epub 2024 May 23.

A case of cytomegalovirus esophagitis difficult to distinguish from Crohn's disease exacerbation

Mika Misaki  1 , Shintaro Sagami  1   2 , Yoko Yamana  2 , Masa Maeda  2 , Aya Hojo  1   2 , Yusuke Miyatani  2 , Ichiro Maeda  3 , Masaru Nakano  1   2 , Toshifumi Hibi  2 , Taku Kobayashi  4   5
Affiliations
Case Reports

A case of cytomegalovirus esophagitis difficult to distinguish from Crohn's disease exacerbation

Mika Misaki et al. Clin J Gastroenterol. 2024 Aug.

Abstract

Patients with Crohn's disease are at higher risk of opportunistic infection, especially if treated with immunosuppressive therapy. Cytomegalovirus has been reported to cause ulcerated lesions mainly in the lower gastrointestinal tract of inflammatory bowel disease patients. We herein report a rare case of Crohn's disease complicated with cytomegalovirus esophagitis, which was difficult to distinguish from exacerbation of Crohn's disease. Diagnostic values of clinical course, blood tests, endoscopic and histological examinations are limited but the present case was therapeutically diagnosed by antiviral therapy in combination with histological evidence of cytomegalovirus.

Keywords: Antiviral therapy; Immunosuppressive therapy; Inflammatory bowel disease; Viral esophagitis.

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