Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Apr 24;13(5):288.
doi: 10.3390/biology13050288.

Chemical Constituents and Their Bioactivities of Plants from the Genus Eupatorium (2015-Present)

Hao Geng  1
Affiliations
Review

Chemical Constituents and Their Bioactivities of Plants from the Genus Eupatorium (2015-Present)

Hao Geng. Biology (Basel). .

Abstract

The genus Eupatorium belongs to the Asteraceae (Compositae) family and has multiple properties, such as invasiveness and toxicity, and is used in folk medicine. The last review on the chemical constituents of this genus and their biological activities was published in 2015. The present review provides an overview of 192 natural products discovered from 2015 to the present. These products include 63 sesquiterpenoids, 53 benzofuran derivatives, 39 thymol derivatives, 15 fatty acids, 7 diterpenoids, 5 monoterpenoids, 4 acetophenones, and 6 other compounds. We also characterized their respective chemical structures and cytotoxic, antifungal, insecticidal, antibacterial, anti-inflammatory, and antinociceptive activities.

Keywords: Eupatorium; biological activities; chemical constituents; natural products; plant-derived natural products.

PubMed Disclaimer

Conflict of interest statement

The author declares no conflicts of interest.

Figures

Figure 1
Figure 1
Classification and proportion of the reviewed natural products from Eupatorium.
Figure 2
Figure 2
The chemical structures isolated from E. adenophorum.
Figure 2
Figure 2
The chemical structures isolated from E. adenophorum.
Figure 3
Figure 3
The chemical structures isolated from E. chinense.
Figure 3
Figure 3
The chemical structures isolated from E. chinense.
Figure 3
Figure 3
The chemical structures isolated from E. chinense.
Figure 4
Figure 4
The chemical structures isolated from E. fortunei.
Figure 4
Figure 4
The chemical structures isolated from E. fortunei.
Figure 4
Figure 4
The chemical structures isolated from E. fortunei.
Figure 4
Figure 4
The chemical structures isolated from E. fortunei.
Figure 5
Figure 5
The chemical structures isolated from E. heterophyllum.
Figure 5
Figure 5
The chemical structures isolated from E. heterophyllum.
Figure 5
Figure 5
The chemical structures isolated from E. heterophyllum.
Figure 6
Figure 6
The chemical structures isolated from E. lindleyanum, E. macrocephalum, and E. obtusissmum.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Wright C.W. Recent developments in research on terrestrial plants used for the treatment of malaria. Nat. Prod. Rep. 2010;27:961–968. doi: 10.1039/c002196m. - DOI - PubMed
    1. Hung H.Y., Qian K.D., Morris-Natschke S.L., Hsuc C.S., Lee K.H. Recent discovery of plant-derived anti-diabetic natural products. Nat. Prod. Rep. 2012;29:580–606. doi: 10.1039/c2np00074a. - DOI - PubMed
    1. Tasneema S., Liu B., Li B., Choudharya M.I., Wang W. Molecular pharmacology of inflammation: Medicinal plants as anti-inflammatory agents. Pharmacol. Res. 2019;139:126–140. doi: 10.1016/j.phrs.2018.11.001. - DOI - PubMed
    1. Cheng G., Ma T.T., Deng Z.H., Gutiérrez-Gamboa G., Ge Q., Xu P.K., Zhang Q.W., Zhang J.X., Meng J.F., Reiter R.J., et al. Plant-derived melatonin from food: A gift of nature. Food Funct. 2021;12:2829–2849. doi: 10.1039/D0FO03213A. - DOI - PubMed
    1. Rahimian N., Miraei H.R., Amiri A., Ebrahimi M.S., Nahand J.S., Tarrahimofrad H., Hamblin M.R., Khan H., Mirzaei H. Plant-based vaccines and cancer therapy: Where are we now and where are we going? Pharmacol. Res. 2021;169:105655. doi: 10.1016/j.phrs.2021.105655. - DOI - PubMed

LinkOut - more resources