Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Apr 25;13(5):352.
doi: 10.3390/pathogens13050352.

Target Antigens in Western and Line Immunoblots for Supporting the Diagnosis of Lyme Disease. Comment on Porwancher et al. Immunoblot Criteria for Diagnosis of Lyme Disease: A Comparison of CDC Criteria to Alternative Interpretive Approaches. Pathogens 2023, 12, 1282

Jyotsna S Shah  1 , Ranjan Ramasamy  1
Affiliations

Target Antigens in Western and Line Immunoblots for Supporting the Diagnosis of Lyme Disease. Comment on Porwancher et al. Immunoblot Criteria for Diagnosis of Lyme Disease: A Comparison of CDC Criteria to Alternative Interpretive Approaches. Pathogens 2023, 12, 1282

Jyotsna S Shah et al. Pathogens. .

Abstract

An article was recently published in Pathogens on using different target antigens from Borrelia species that cause Lyme disease for detecting serum antibodies to support a clinical diagnosis of Lyme disease (LD) [...].

PubMed Disclaimer

Conflict of interest statement

The authors are affiliated with IGeneX, which is an accredited laboratory for performing laboratory tests of tick-borne diseases, including Lyme disease.

Comment on

  • Pathogens. 12:1282.

Similar articles

See all similar articles

References

    1. Porwancher R., Levin A., Trevejo R. Immunoblot criteria for diagnosis of Lyme disease: A comparison of CDC criteria to alternative interpretive approaches. Pathogens. 2023;12:1282. doi: 10.3390/pathogens12111282. - DOI - PMC - PubMed
    1. Centers for Disease Control and Prevention Notice to readers: Recommendations for test performance and interpretation from the second national conference on serologic diagnosis of Lyme disease. Morb. Mortal. Wkly. Rep. 1995;44:590–591. - PubMed
    1. Shah J.S., Du Cruz I., Narciso W., Lo W., Harris N.S. Improved clinical sensitivity for detection of antibodies to Borrelia burgdorferi by Western blots prepared from a mixture of two strains of B. burgdorferi, 297 and B31, and interpreted by in-house criteria. Eur. Infect. Dis. 2010;4:56–60.
    1. Shah J.S., Du Cruz I., Narciso W., Lo W., Harris N.S. Improved sensitivity of Lyme disease western blots prepared with a mixture of Borrelia burgdorferi strains 297 and B31. Chronic Dis. Int. 2014;1:7.
    1. Liu S., Du Cruz I., Ramos C.C., Taleon P., Ramasamy R., Shah J. Pilot study of immunoblots with recombinant Borrelia burgdorferi antigens for laboratory diagnosis of Lyme disease. Healthcare. 2018;6:99. doi: 10.3390/healthcare6030099. - DOI - PMC - PubMed