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. 2024 May 23;187(11):2628-2632.
doi: 10.1016/j.cell.2024.04.028.

What comes next in glycobiology

Peter H Seeberger, Yun Ge, Christine M Szymanski, Daniel Kolarich, Morten Thaysen-Andersen, Nicolle H Packer, Elisa Fadda, Benjamin Davis, Shoko Nishihara, Gabriel A Rabinovich, Peter D Kwong, Richard Strasser
Free article

What comes next in glycobiology

Peter H Seeberger et al. Cell. .
Free article

Abstract

Glycans, with their variable compositions and highly dynamic conformations, vastly expand the heterogeneity of whatever factor or cell they are attached to. These properties make them crucial contributors to biological function and organismal health and also very difficult to study. That may be changing as we look to the future of glycobiology.

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Conflict of interest statement

Declaration of interests B.G.D. is a shareholder of SugaROx and holds various patents that seek to exploit the function of glycosylation and that would afford him royalties upon exploitation. G.A.R. is co-founder of Galtec SAS and co-inventor on a family of US and European patents associated with therapeutic and diagnostic applications of galectins in cancer and autoimmune and inflammatory conditions. P.H.S. has a significant financial interest in GlycoUniverse GmbH&CoKG (commercializing the automated synthesis technology and services related to it) and Tacalyx GmbH (developing anti-glycan antibodies to treat cancer patients) as well as advisory roles with both companies. He holds a host of patents in the area of synthetic carbohydrates and their use as vaccines and for the generation of therapeutic antibodies.

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