Neonatal spindle-cell CD34-positive plaque-like tumour: a new entity characterised by NTRK gene fusion

. 2024 Oct;485(4):729-733.

doi: 10.1007/s00428-024-03831-7. Epub 2024 May 24.

P Drabent¹, T Kervarrec^{2

3}, A Tallet⁴, S Fraitag⁵

Affiliations

¹ Department of Pathology, Hôpital Universitaire Necker-Enfants Malades, APHP, Paris, France. philippe.drabent@aphp.fr.
² Department of Pathology, Centre Hospitalier Universitaire de Tours, Université de Tours, Tours, France.
³ "Biologie Des Infections À Polyomavirus" Team, UMR INRAE ISP 1282, Université de Tours, Tours, France.
⁴ Platform of Somatic Tumor Molecular Genetics, Centre Hospitalier Universitaire de Tours, Tours, France.
⁵ Department of Pathology, Hôpital Universitaire Necker-Enfants Malades, APHP, Paris, France.

P Drabent et al. Virchows Arch. 2024 Oct.

. 2024 Oct;485(4):729-733.

doi: 10.1007/s00428-024-03831-7. Epub 2024 May 24.

P Drabent¹, T Kervarrec^{2

3}, A Tallet⁴, S Fraitag⁵

¹ Department of Pathology, Hôpital Universitaire Necker-Enfants Malades, APHP, Paris, France. philippe.drabent@aphp.fr.
² Department of Pathology, Centre Hospitalier Universitaire de Tours, Université de Tours, Tours, France.
³ "Biologie Des Infections À Polyomavirus" Team, UMR INRAE ISP 1282, Université de Tours, Tours, France.
⁴ Platform of Somatic Tumor Molecular Genetics, Centre Hospitalier Universitaire de Tours, Tours, France.
⁵ Department of Pathology, Hôpital Universitaire Necker-Enfants Malades, APHP, Paris, France.

No abstract available

References

1. Antonescu CR, Dickson BC, Swanson D, Zhang L, Sung YS, Kao YC, Chang WC, Ran L, Pappo A, Bahrami A, Chi P, Fletcher CD (2019) Spindle cell tumors with RET gene fusions exhibit a morphologic spectrum akin to tumors with NTRK gene fusions. Am J Surg Pathol 43(10):1384–1391. https://doi.org/10.1097/PAS.0000000000001297 - DOI - PubMed - PMC
1. Rodríguez-Jurado R, Palacios C, Durán-McKinster C, Mercadillo P, Orozco-Covarrubias L, Saez-De-Ocariz MDM, Ruiz-Maldonado R (2004) Medallion-like dermal dendrocyte hamartoma: a new clinically and histopathologically distinct lesion. J Am Acad Dermatol 51:359–363 - DOI - PubMed
1. Kutzner H, Mentzel T, Palmedo G, Hantschke M, Rütten A, Paredes BE, Schärer L, Guillen CS, Requena L (2010) Plaque-like CD34-positive dermal fibroma (“medallion-like dermal dendrocyte hamartoma”): clinicopathologic, immunohistochemical, and molecular analysis of 5 cases emphasizing its distinction from superficial, plaque-like dermatofibrosarcoma protuberans. Am J Surg Pathol 34(2):190–201. https://doi.org/10.1097/PAS.0b013e3181c7cf11 - DOI - PubMed
1. de Feraudy S, Fletcher CD (2012) Fibroblastic connective tissue nevus: a rare cutaneous lesion analyzed in a series of 25 cases. Am J Surg Pathol 36(10):1509–1515. https://doi.org/10.1097/PAS.0b013e31825e63bf - DOI - PubMed
1. Drabent P, Fraitag S (2021) Update on superficial spindle cell mesenchymal tumors in children. Dermatopathology (Basel) 8(3):285–300 - DOI - PubMed