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Review
. 2024 Apr 24;14(5):540.
doi: 10.3390/life14050540.

Immunological and Clinical Responses to Vaccinations among Adults Living with HIV

Carlo Bieńkowski  1   2 , Zuzanna Żak  3 , Filip Fijołek  1   2 , Martyna Cholewik  4 , Maciej Stępień  4 , Agata Skrzat-Klapaczyńska  1   2 , Justyna D Kowalska  1   2
Affiliations
Review

Immunological and Clinical Responses to Vaccinations among Adults Living with HIV

Carlo Bieńkowski et al. Life (Basel). .

Abstract

People living with human immunodeficiency virus (HIV) are at higher risk of morbidity and mortality due to vaccine-preventable diseases. At the same time, they are less likely to respond to vaccinations, and might have a higher rate of vaccine adverse event and faster waning of protective effect. International and national guidelines emphasize the importance of vaccinating people living with HIV against respiratory system disease pathogens including seasonal influenza, Streptococcus pneumoniae, and COVID-19, as well as against sexually transmitted infections, i.e., Hepatitis A and B (HAV, HBV) and human papillomavirus (HPV). This narrative review aims to provide a comprehensive examination of the current knowledge regarding the immune and clinical responses elicited by vaccinations in the older adult population living with HIV.

Keywords: HIV; prevention; vaccinations.

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Conflict of interest statement

The authors declare no conflicts of interest.

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