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. 2024 Oct 1;118(10):639-641.
doi: 10.1093/trstmh/trae036.

Rectal artesunate: lives not saved

N J White  1   2 , T Peto  1   2 , J A Watson  2   3
Affiliations

Rectal artesunate: lives not saved

N J White et al. Trans R Soc Trop Med Hyg. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

None declared.

Figures

Figure 1.
Figure 1.
Estimates of severe malaria lives saved based on global procurement information under the following assumptions: (a) for parenteral artesunate, the number of patients needed to treat to save one life was 42, and the average dose used was five vials, of which one-half was used to treat suspected severe malaria; and (b) for rectal artesunate, the context of use was similar to that in the large randomised trial, the average number of RASs used was 1.5 (i.e. an equal split in ages between <3 y [one suppository] and >3 y [two suppositories) and the number of patients needed to treat to save one life was 241.
See this image and copyright information in PMC

References

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    1. Malaria Policy Advisory Group . WHO Malaria Policy Advisory Group (MPAG) Meeting Report, 18–20 April 2023. World Health Organisation; 2023. Available from: https://www.who.int/publications/i/item/9789240074385 [accessed 1 March 2024].
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