Further studies on the influence of interferon on pokeweed mitogen induced Ig-synthesis in vitro
- PMID: 3879504
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Further studies on the influence of interferon on pokeweed mitogen induced Ig-synthesis in vitro
J Clin Lab Immunol.
1985 Dec.
Abstract
Preincubation with pure interferon beta, but not partially purified interferon alpha, increased immunoglobulin production from non-fractionated peripheral blood mononuclear cells stimulated by pokeweed mitogen. Preincubation of B lymphocytes, but not T lymphocytes or monocytes, with pure interferon beta also increased immunoglobulin synthesis. It is concluded that interferon has a direct effect on B lymphocytes in enhancing immunoglobulin production.
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