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Review
. 2024 Jul;26(7):249-262.
doi: 10.1007/s11883-024-01207-5. Epub 2024 May 25.

The Role of Sleep in Cardiovascular Disease

Vita N Jaspan  1 , Garred S Greenberg  1 , Siddhant Parihar  1 , Christine M Park  1 , Virend K Somers  2 , Michael D Shapiro  3 , Carl J Lavie  4 , Salim S Virani  5   6   7 , Leandro Slipczuk  8
Affiliations
Review

The Role of Sleep in Cardiovascular Disease

Vita N Jaspan et al. Curr Atheroscler Rep. 2024 Jul.

Abstract

Purpose of review: Sleep is an important component of cardiovascular (CV) health. This review summarizes the complex relationship between sleep and CV disease (CVD). Additionally, we describe the data supporting the treatment of sleep disturbances in preventing and treating CVD.

Recent findings: Recent guidelines recommend screening for obstructive sleep apnea in patients with atrial fibrillation. New data continues to demonstrate the importance of sleep quality and duration for CV health. There is a complex bidirectional relationship between sleep health and CVD. Sleep disturbances have systemic effects that contribute to the development of CVD, including hypertension, coronary artery disease, heart failure, and arrhythmias. Additionally, CVD contributes to the development of sleep disturbances. However, more data are needed to support the role of screening for and treatment of sleep disorders for the prevention of CVD.

Keywords: Cardiovascular disease; Obstructive sleep apnea; Prevention; Sleep.

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Conflict of interest statement

Leandro Slipczuk is supported by institutional grants from Amgen and Philips. Salim Virani is supported by research grants from the NIH, UK NIHR, US Department of Veterans Affairs and research endowments from the Tahir and Jooma Family and Asharia Family. Additionally, Dr. Virani serves as a section editor for Current Atherosclerosis Reports. Michael D. Shapiro is supported by institutional grants from Amgen, Boehringer Ingelheim, 89Bio, Esperion, Genentech, Novartis, Ionis, Merck, and New Amsterdam. He has participated in Scientific Advisory Boards with Amgen, Agepha, Ionis, Novartis, New Amsterdam, and Merck. He has served as a consultant for Ionis, Novartis, Regeneron, Aidoc, Shanghai Pharma Biotherapeutics, Kaneka, and Novo Nordisk. Virend K Somers is supported by NIH HL65176 and NIH HL160619. He is a consultant for Jazz Pharma, Axsome, Know Labs, Lilly and ApniMed and serves on the Sleep Number Scientific Advisory Board. The remaining authors have nothing to disclose.

Figures

Fig. 1
Fig. 1
Central Illustration- Overview of the links between sleep health and cardiovascular health. OSA obstructive sleep apnea, CAD coronary artery disease, CV cardiovascular. Created with BioRender.com. Central illustration demonstrating the links between sleep health and cardiovascular health. OSA = obstructive sleep apnea, CAD = coronary artery disease, CV = cardiovascular
See this image and copyright information in PMC

References

    1. Unraveling why we sleep: Quantitative analysis reveals abrupt transition from neural reorganization to repair in early development | Science Advances. 10.1126/sciadv.aba0398. Accessed 20 Feb 2024 - PMC - PubMed
    1. Tsao CW, Aday AW, Almarzooq ZI, et al. Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association. Circulation. 2023;147:e93–e621. doi: 10.1161/CIR.0000000000001123. - DOI - PubMed
    1. • Lloyd-Jones DM, Allen NB, Anderson CAM, et al. Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association. Circulation. 2022;146(5):e18–e43. Presidential advisory from the AHA updating the AHA construct of CV health from "Life’s Simple 7" to "Life’s Essential 8." - PMC - PubMed
    1. Yang X, Chen H, Li S, Pan L, Jia C. Association of Sleep Duration with the Morbidity and Mortality of Coronary Artery Disease: A Meta-analysis of Prospective Studies. Heart Lung Circ. 2015;24:1180–1190. doi: 10.1016/j.hlc.2015.08.005. - DOI - PubMed
    1. Makarem N, Castro-Diehl C, St-Onge M, Redline S, Shea S, Lloyd-Jones D, Ning H, Aggarwal B. Redefining Cardiovascular Health to Include Sleep: Prospective Associations With Cardiovascular Disease in the MESA Sleep Study. J Am Heart Assoc. 2022;11:e025252. doi: 10.1161/JAHA.122.025252. - DOI - PMC - PubMed

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