Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985;48(1-6):111-6.
doi: 10.1159/000101113.

Bioengineering changes in spastic cerebral palsy groups following cerebellar stimulation

R Davis, E Gray, T Ryan, J Schulman

Bioengineering changes in spastic cerebral palsy groups following cerebellar stimulation

R Davis et al. Appl Neurophysiol. 1985.

Abstract

Quantitative bioengineering tests were performed on 30 spastic cerebral palsy (CP) patients who underwent chronic cerebellar stimulation (CCS) using the fully implantable pulse generator (Neurolith 601, 1.1-1.8 microC/cm2/phase). Using respiratory inductive plethysmography to measure 8 patients with paroxysmal and/or ataxic breathing patterns, 5 were shown to revert to normal with 3 others markedly improved within 5 months of CCS. Compliance testing of the ankle was performed on 4 patients who showed improvement in 9 of the 16 tests performed. Motor performance ability was evaluated with 9 comprehensive tests in 17 patients. Following 1-2 weeks of CCS, 52% showed performance increases greater than 10%, increasing to 62% during the first year.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

  • A Brief History of Cerebellar Neurostimulation.
    Ponce GV, Klaus J, Schutter DJLG. Ponce GV, et al. Cerebellum. 2022 Aug;21(4):715-730. doi: 10.1007/s12311-021-01310-2. Epub 2021 Aug 17. Cerebellum. 2022. PMID: 34403075 Free PMC article. Review.
  • Neuromodulation: What the neurointerventionalist needs to know.
    Mensah-Brown KG, Naylor RM, Graepel S, Brinjikji W. Mensah-Brown KG, et al. Interv Neuroradiol. 2024 Mar 8:15910199231224554. doi: 10.1177/15910199231224554. Online ahead of print. Interv Neuroradiol. 2024. PMID: 38454831 Free PMC article.
  • Dystonia and Cerebellum: From Bench to Bedside.
    Morigaki R, Miyamoto R, Matsuda T, Miyake K, Yamamoto N, Takagi Y. Morigaki R, et al. Life (Basel). 2021 Jul 31;11(8):776. doi: 10.3390/life11080776. Life (Basel). 2021. PMID: 34440520 Free PMC article. Review.
  • Consensus Paper: Experimental Neurostimulation of the Cerebellum.
    Miterko LN, Baker KB, Beckinghausen J, Bradnam LV, Cheng MY, Cooperrider J, DeLong MR, Gornati SV, Hallett M, Heck DH, Hoebeek FE, Kouzani AZ, Kuo SH, Louis ED, Machado A, Manto M, McCambridge AB, Nitsche MA, Taib NOB, Popa T, Tanaka M, Timmann D, Steinberg GK, Wang EH, Wichmann T, Xie T, Sillitoe RV. Miterko LN, et al. Cerebellum. 2019 Dec;18(6):1064-1097. doi: 10.1007/s12311-019-01041-5. Cerebellum. 2019. PMID: 31165428 Free PMC article. Review.