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Case Reports
. 2024 Aug;35(8):1581-1584.
doi: 10.1007/s00192-024-05819-y. Epub 2024 May 27.

Microbiologist in the Clinic: Postmenopausal Woman with Chronic OAB and Positive Urine Culture

Affiliations
Case Reports

Microbiologist in the Clinic: Postmenopausal Woman with Chronic OAB and Positive Urine Culture

Linda Brubaker et al. Int Urogynecol J. 2024 Aug.

Abstract

In this second episode of the Microbiologist in the Clinic series, clinicians and laboratory scientists share their perspectives about a 75-year-old woman who was diagnosed with asymptomatic bacteriuria based on positive urine cultures. The patient and her GP are concerned about this laboratory finding as the patient will become immunosuppressed with planned chemotherapy. The patient has had an overactive bladder (OAB) for approximately 20 years, with good control of her urinary urgency and frequency (no incontinence) with a stable dose of OAB medication. The challenges of this clinical presentation are discussed, with evidence for evaluation and treatment.

Keywords: Antibiotics; Lower urinary tract symptoms; Microbiome; Overactive bladder; Pyuria; UTI; Urobiome; Women’s health.

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References

    1. Abraham SN, Miao Y. The nature of immune responses to urinary tract infections. Nat Rev Immunol. 2015;15(10):655–63. https://doi.org/10.1038/nri3887 . - DOI - PubMed - PMC
    1. Falagas ME, Kotsantis IK, Vouloumanou EK, Rafailidis PI. Antibiotics versus placebo in the treatment of women with uncomplicated cystitis: a meta-analysis of randomized controlled trials. J Infect. 2009;58(2):91–102. https://doi.org/10.1016/j.jinf.2008.12.009 . - DOI - PubMed
    1. Nielsen KL, Dynesen P, Larsen P, Frimodt-Møller N. Faecal Escherichia coli from patients with E. coli urinary tract infection and healthy controls who have never had a urinary tract infection. J Med Microbiol. 2014;63(4):582–9. https://doi.org/10.1099/jmm.0.068783-0 . - DOI - PubMed
    1. Hayes BW, Abraham SN. Innate immune responses to bladder infection. Microbiol Spectr. 2016;4(6). https://doi.org/10.1128/microbiolspec.uti-0024-2016 .
    1. Sarkissian Milner CA, Alteri CJ, Mobley HLT. UTI patients have pre-existing antigen-specific antibody titers against UTI vaccine antigens. Vaccine. 2019;37(35):4937–46. https://doi.org/10.1016/j.vaccine.2019.07.031 . - DOI

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