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Case Reports
. 2024 May 28;62(11):e244-e246.
doi: 10.1515/cclm-2024-0465. Print 2024 Oct 28.

Methemoglobinemia after sodium nitrite poisoning: what blood gas analysis tells us (and what it might not)

Fabrizio Cappellini  1 , Chiara Fania  1 , Loredana Di Simone  2 , Francesco Gaiani  3 , Marco Giani  3   2 , Marco Casati  1
Affiliations
Case Reports

Methemoglobinemia after sodium nitrite poisoning: what blood gas analysis tells us (and what it might not)

Fabrizio Cappellini et al. Clin Chem Lab Med. .
No abstract available

Keywords: POCT; methemoglobin; sodium nitrite.

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References

    1. Gaiani, F, Giani, M, Vergnano, B, Sardella, J, Cappellini, F, Casati, M, et al.. Extracorporeal cardio-pulmonary resuscitation in a patient with missed diagnosis of sodium nitrite intoxication. Perfusion 2024. https://doi.org/10.1177/02676591241240036 [Epub ahead of print].
    1. Grubina, R, Huang, Z, Shiva, S, Joshi, MS, Azarov, I, Basu, S, et al.. Concerted nitric oxide formation and release from the simultaneous reactions of nitrite with deoxy- and oxyhemoglobin. J Biol Chem 2007;282:12916–27. https://doi.org/10.1074/jbc.m700546200 . - DOI
    1. Hikin, LJ, Ho, J, Ahluwalia, A, Smith, PR. Sodium nitrite poisoning: a series of 20 fatalities in which post-mortem blood nitrite and nitrate concentrations are reported. Forensic Sci Int 2023;345:1–7.
    1. Albano, GD, La Spina, C, Buscemi, R, Palmeri, M, Malandrino, G, Licciardello, F, et al.. Systematic review of fatal sodium nitrite ingestion cases: toxicological and forensic implications. Toxics 2024;12:1–16. https://doi.org/10.3390/toxics12020124 . - DOI
    1. Minyoul, K, Suncheun, K, Wonkyung, Y, Juhyun, S. Determination of nitrite and nitrate in postmortem whole blood samples of 10 sodium nitrite poisoning cases: the importance of nitrate in determining nitrite poisoning. Forensic Sci Int 2022;335:1–6.

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