Treponemal point-of-care tests for syphilis

doi:10.1503/cmaj.231548

. 2024 May 26;196(20):E702-E703.

doi: 10.1503/cmaj.231548.

Treponemal point-of-care tests for syphilis

Andrea D Chittle¹, Paul Sandstrom², Joseph Cox², Raymond S W Tsang²

Affiliations

¹ Centre for Communicable Diseases and Infection Control (Chittle), Public Health Agency of Canada, Ottawa, Ont.; Department of Family Medicine (Chittle), Faculty of Health Sciences, McMaster University, Hamilton, Ont.; National Microbiology Laboratory Branch (Sandstrom, Tsang), Public Health Agency of Canada; Department of Medical Microbiology and Infectious Diseases (Sandstrom), Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Epidemiology, Biostatistics and Occupational Health (Cox), School of Population and Global Health, McGill University, Montréal, Que. andrea.chittle@phac-aspc.gc.ca.
² Centre for Communicable Diseases and Infection Control (Chittle), Public Health Agency of Canada, Ottawa, Ont.; Department of Family Medicine (Chittle), Faculty of Health Sciences, McMaster University, Hamilton, Ont.; National Microbiology Laboratory Branch (Sandstrom, Tsang), Public Health Agency of Canada; Department of Medical Microbiology and Infectious Diseases (Sandstrom), Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Epidemiology, Biostatistics and Occupational Health (Cox), School of Population and Global Health, McGill University, Montréal, Que.

PMID: 38802133
PMCID: PMC11142022
DOI: 10.1503/cmaj.231548

Treponemal point-of-care tests for syphilis

Andrea D Chittle et al. CMAJ. 2024.

. 2024 May 26;196(20):E702-E703.

doi: 10.1503/cmaj.231548.

Authors

Andrea D Chittle¹, Paul Sandstrom², Joseph Cox², Raymond S W Tsang²

Affiliations

¹ Centre for Communicable Diseases and Infection Control (Chittle), Public Health Agency of Canada, Ottawa, Ont.; Department of Family Medicine (Chittle), Faculty of Health Sciences, McMaster University, Hamilton, Ont.; National Microbiology Laboratory Branch (Sandstrom, Tsang), Public Health Agency of Canada; Department of Medical Microbiology and Infectious Diseases (Sandstrom), Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Epidemiology, Biostatistics and Occupational Health (Cox), School of Population and Global Health, McGill University, Montréal, Que. andrea.chittle@phac-aspc.gc.ca.
² Centre for Communicable Diseases and Infection Control (Chittle), Public Health Agency of Canada, Ottawa, Ont.; Department of Family Medicine (Chittle), Faculty of Health Sciences, McMaster University, Hamilton, Ont.; National Microbiology Laboratory Branch (Sandstrom, Tsang), Public Health Agency of Canada; Department of Medical Microbiology and Infectious Diseases (Sandstrom), Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Epidemiology, Biostatistics and Occupational Health (Cox), School of Population and Global Health, McGill University, Montréal, Que.

PMID: 38802133
PMCID: PMC11142022
DOI: 10.1503/cmaj.231548

Erratum in

Correction to "Treponemal point-of-care tests for syphilis".
[No authors listed] [No authors listed] CMAJ. 2024 Jun 16;196(23):E793. doi: 10.1503/cmaj.240781. CMAJ. 2024. PMID: 38885983 Free PMC article. No abstract available.

No abstract available

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Conflict of interest statement

Competing interests:: Andrea Chittle worked on this manuscript in the course of her paid employment with the Public Health Agency of Canada. Joseph Cox reports grants or contracts from ViiV Healthcare and Gilead Canada, and consulting fees, honoraria, and support for attending meetings from ViiV Healthcare. Raymond Tsang performs laboratory and field evaluations of syphilis point-of-care tests. No other competing interests were declared.

Cited by

The rise of congenital syphilis in Canada: threats and opportunities.
Tetteh A, Moore V. Tetteh A, et al. Front Public Health. 2025 Jan 22;12:1522698. doi: 10.3389/fpubh.2024.1522698. eCollection 2024. Front Public Health. 2025. PMID: 39911782 Free PMC article. Review.
Correction to "Treponemal point-of-care tests for syphilis".
[No authors listed] [No authors listed] CMAJ. 2024 Jun 16;196(23):E793. doi: 10.1503/cmaj.240781. CMAJ. 2024. PMID: 38885983 Free PMC article. No abstract available.

References

1. Syphilis Guide in Sexually transmitted and blood-borne infections: guides for health professionals. Ottawa: Public Health Agency of Canada; modified 2024 Jan. 5. Available: https://www.canada.ca/en/public-health/services/infectious-diseases/sexu... (accessed 2023 Dec. 7).
1. Robinson JL. Canadian Paediatric Society, Infectious Diseases and Immunization Committee. Congenital syphilis: no longer just of historical interest [position statement]. Canadian Paediatric Society; 2009, updated 2018 Feb. 8, reaffirmed 2018 Feb. 28. Available: https://cps.ca/en/documents/position/congenital-syphilis1 (accessed 2023 Nov. 22).
1. Naidu P, Tsang RSW. Canadian Public Health Laboratory Network guidelines for the use of point-of-care tests for Treponema pallidum in Canada. J Assoc Med Microbiol Infect Dis Can 2022;7:85–96. - PMC - PubMed
1. Singh AE, Ives N, Gratrix J, et al. . PoSH Study Team. Sensitivity and specificity of two investigational Point of care Tests for Syphilis and HIV (PoSH Study) for the diagnosis and treatment of infectious syphilis in Canada: a cross sectional study. Clin Microbiol Infect 2023;29:940.e1–7. - PubMed
1. WHO information note on the use of dual HIV/syphilis rapid diagnostic tests (RDT). Geneva: World Health Organization (WHO); 2017:1–8. Available: https://www.paho.org/en/documents/who-information-note-use-dual-hivsyphi... (accessed 2023 Nov. 25).

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[1] Syphilis Guide in Sexually transmitted and blood-borne infections: guides for health professionals. Ottawa: Public Health Agency of Canada; modified 2024 Jan. 5. Available: https://www.canada.ca/en/public-health/services/infectious-diseases/sexu... (accessed 2023 Dec. 7).

[2] Syphilis Guide in Sexually transmitted and blood-borne infections: guides for health professionals. Ottawa: Public Health Agency of Canada; modified 2024 Jan. 5. Available: https://www.canada.ca/en/public-health/services/infectious-diseases/sexu... (accessed 2023 Dec. 7).

[3] Robinson JL. Canadian Paediatric Society, Infectious Diseases and Immunization Committee. Congenital syphilis: no longer just of historical interest [position statement]. Canadian Paediatric Society; 2009, updated 2018 Feb. 8, reaffirmed 2018 Feb. 28. Available: https://cps.ca/en/documents/position/congenital-syphilis1 (accessed 2023 Nov. 22).

[4] Robinson JL. Canadian Paediatric Society, Infectious Diseases and Immunization Committee. Congenital syphilis: no longer just of historical interest [position statement]. Canadian Paediatric Society; 2009, updated 2018 Feb. 8, reaffirmed 2018 Feb. 28. Available: https://cps.ca/en/documents/position/congenital-syphilis1 (accessed 2023 Nov. 22).

[5] Naidu P, Tsang RSW. Canadian Public Health Laboratory Network guidelines for the use of point-of-care tests for Treponema pallidum in Canada. J Assoc Med Microbiol Infect Dis Can 2022;7:85–96. - PMC - PubMed

[6] Naidu P, Tsang RSW. Canadian Public Health Laboratory Network guidelines for the use of point-of-care tests for Treponema pallidum in Canada. J Assoc Med Microbiol Infect Dis Can 2022;7:85–96. - PMC - PubMed

[7] Singh AE, Ives N, Gratrix J, et al. . PoSH Study Team. Sensitivity and specificity of two investigational Point of care Tests for Syphilis and HIV (PoSH Study) for the diagnosis and treatment of infectious syphilis in Canada: a cross sectional study. Clin Microbiol Infect 2023;29:940.e1–7. - PubMed

[8] Singh AE, Ives N, Gratrix J, et al. . PoSH Study Team. Sensitivity and specificity of two investigational Point of care Tests for Syphilis and HIV (PoSH Study) for the diagnosis and treatment of infectious syphilis in Canada: a cross sectional study. Clin Microbiol Infect 2023;29:940.e1–7. - PubMed

[9] WHO information note on the use of dual HIV/syphilis rapid diagnostic tests (RDT). Geneva: World Health Organization (WHO); 2017:1–8. Available: https://www.paho.org/en/documents/who-information-note-use-dual-hivsyphi... (accessed 2023 Nov. 25).

[10] WHO information note on the use of dual HIV/syphilis rapid diagnostic tests (RDT). Geneva: World Health Organization (WHO); 2017:1–8. Available: https://www.paho.org/en/documents/who-information-note-use-dual-hivsyphi... (accessed 2023 Nov. 25).

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Treponemal point-of-care tests for syphilis

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