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. 2024 May 15;26(5):476-480.
doi: 10.7499/j.issn.1008-8830.2311149.

[Control status and follow-up of acute attacks in children with bronchial asthma with normal pulmonary ventilation function]

[Article in Chinese]
Lan-Lan Ma  1 , Ling Chen  1 , Qin Wang  1 , Yang-Guang Xu  1 , Xing Chen  1
Affiliations

[Control status and follow-up of acute attacks in children with bronchial asthma with normal pulmonary ventilation function]

[Article in Chinese]
Lan-Lan Ma et al. Zhongguo Dang Dai Er Ke Za Zhi. .

Abstract
in English, Chinese

Objectives: To investigate the control status of bronchial asthma (referred to as "asthma") in school-age children with normal pulmonary ventilation function and the occurrence of acute attacks within 1 year of follow-up.

Methods: A retrospective analysis was conducted on clinical data of 327 children aged 6-14 years with bronchial asthma and normal pulmonary ventilation function from April to September 2021. Based on the measured value of one second rate (FEV1/FVC), the children were divided into the ≥80% group (267 cases) and the <80% group (60 cases). The pulmonary ventilation function, asthma control level, and occurrence of acute attacks within 1 year were compared between the two groups.

Results: The baseline pulmonary ventilation function in the <80% group was lower than that in the ≥80% group, and the proportion of small airway dysfunction was higher than that in the ≥80% group (P<0.05). After standardized treatment for 1 year, the small airway function indices in the <80% group improved but remained lower than those in the ≥80% group (P<0.05). The rate of incomplete asthma control at baseline was 34.6% (113/327), and the asthma control level in the <80% group was lower than that in the ≥80% group (P<0.05). After standardized treatment for 1 year, the asthma control level in the <80% group remained lower than that in the ≥80% group, and the proportion of acute asthma attacks was higher than that in the ≥80% group (P<0.05).

Conclusions: Approximately one-third of school-age children with asthma still have incomplete asthma control when their pulmonary ventilation function is normal. Among them, children with measured FEV1/FVC<80% have an increased risk of acute asthma attacks and require close follow-up and strengthened asthma management.

目的: 探讨学龄期肺通气功能正常的支气管哮喘（简称“哮喘”）患儿病情控制情况及随访1年内急性发作情况。方法: 回顾性分析2021年4—9月327例6~14岁肺通气功能正常哮喘患儿临床资料。根据一秒率实测值，分为≥80%组（267例）和<80%组（60例），比较两组肺通气功能、哮喘控制水平差异，以及随访1年急性发作情况。结果: <80%组基线肺通气功能低于≥80%组，小气道功能障碍比例高于≥80%组（P<0.05）；规范治疗1年后，<80%组小气道功能指标均改善，但仍低于≥80%组（P<0.05）。入组时哮喘未完全控制率为34.6%（113/327），<80%组哮喘控制水平低于≥80%组（P<0.05）；规范治疗1年后，<80%组哮喘控制水平仍低于≥80%组，且哮喘急性发作比例高于≥80%组（P<0.05）。结论: 学龄期哮喘患儿在肺通气功能正常时，仍有约1/3为哮喘未完全控制，其中一秒率实测值低于80%的患儿哮喘急性发作风险增加，需密切随访，强化哮喘管理。.

Keywords: Asthma control; Bronchial asthma; Child; Pulmonary ventilatory function.

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Conflict of interest statement

所有作者声明无利益冲突。

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