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Review
. 2024 Jul;64(7):546-552.
doi: 10.1007/s00117-024-01319-8. Epub 2024 May 28.

[Pulmonary neuroendocrine tumors : Current review]

[Article in German]
Affiliations
Review

[Pulmonary neuroendocrine tumors : Current review]

[Article in German]
Hans-Jonas Meyer et al. Radiologie (Heidelb). 2024 Jul.

Abstract

Clinical issue: Neuroendocrine neoplasms of the lung are a heterogenous tumor group. The pathological classification comprises diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, classic neuroendocrine tumors, and neuroendocrine carcinoma. Classic neuroendocrine tumors include typical and atypical carcinoid tumors.

Diagnostic work-up: Imaging plays an important role in diagnosis and can help in identifying the tumor biology. Overall, this tumor group is rare, comprising less than 2% of all thoracic tumors.

Practical recommendations: In the current review, the various tumors are presented and important aspects regarding pathological classification, imaging modalities, and treatment are described.

Zusammenfassung: KLINISCHES PROBLEM: Die neuroendokrinen Neoplasien der Lunge stellen eine heterogene Gruppe von Tumoren dar. Die pathologische Einteilung enthält die diffuse idiopathische neuroendokrine Zellhyperplasie, die klassischen neuroendokrinen Tumoren und das neuroendokrine Karzinom. Die klassischen neuroendokrinen Tumoren beinhalten das typische und atypische Karzinoid.

Diagnostik: Die Bildgebung hat einen wichtigen Anteil an der Diagnosestellung der Tumoren und kann helfen, die Tumorbiologie widerzuspiegeln. Insgesamt sind die Tumoren selten mit einer Frequenz von nur weniger als 2 % aller thorakaler Tumoren. EMPFEHLUNG FüR DIE PRAXIS: Der vorliegende Artikel stellt die verschiedenen Tumoren dar und beinhaltet die wichtigen Aspekte der pathologischen Einteilung, der Bildgebung und der Therapie.

Keywords: Carcinoid tumor; Computed tomography; Neuroendocrine neoplasia; Positron emission tomography; Radiomics.

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References

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