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Review
. 2024 Jun;31(26):38061-38082.
doi: 10.1007/s11356-024-33712-0. Epub 2024 May 28.

Advancements in sunscreen formulations: integrating polyphenolic nanocarriers and nanotechnology for enhanced UV protection

Aswathi Raju Hegde  1 , Manisha Uday Kunder  2 , Megha Narayanaswamy  2 , Shruthi Murugesan  2 , Sharon Caroline Furtado  2 , Basavaraj Basappa Veerabhadraiah  2 , Bharath Srinivasan  2
Affiliations
Review

Advancements in sunscreen formulations: integrating polyphenolic nanocarriers and nanotechnology for enhanced UV protection

Aswathi Raju Hegde et al. Environ Sci Pollut Res Int. 2024 Jun.

Abstract

Sunscreens are essential in protecting the skin from harmful effects of ultraviolet radiation (UVR). These formulations, designed to absorb, block, or scatter UVR, offer vital protection against skin aging, sunburns, and the development of skin cancers like melanomas. However, some sunscreens, especially those containing organic/chemical compounds, can cause allergic reactions. To address this, researchers are extensively investigating formulations that incorporate plant extracts rich in polyphenols, such as flavonoids and carotenoids, which can be considered safer alternatives. Products derived from plants are commonly used in cosmetics to counteract skin aging due to their antioxidant activity that combat harmful free radicals. This review focuses on evaluating the advancements in chemical and natural sunscreens, exploring the integration of polyphenolic nanocarriers within sunscreen formulas, their interaction with UVR, and utilizing nanotechnology to enhance their effectiveness. An attempt has been made to highlight the concerns related to toxicity associated with their use and notable advancements in the regulatory aspects governing their utilization.

Keywords: Cosmetics; Nanocarrier; Nanotechnology; Polyphenols; Skin; Sunscreen; Ultraviolet radiation.

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References

    1. Addor FAS (2017) Antioxidants in dermatology. An Bras Dermatol 92(3):356–362. https://doi.org/10.1590/abd1806-4841.20175697 - DOI
    1. Adler BL, DeLeo VA (2020) Sunscreen safety: a review of recent studies on humans and the environment. Current Dermatology Reports 9:1–9 - DOI
    1. Antoniou C, Kosmadaki MG, Stratigos AJ, Katsambas AD (2008) Sunscreens–what’s important to know. J Eur Acad Dermatol Venereol 22(9):1110–1119 - DOI
    1. Aquino RP (2012) Nanoemulsions for delivery of benzophenone 3. J Nanosci Nanotechnol 12(2):1252–1259
    1. Arianto A, Bangun H, Sumaiyah, Yanti Putri Siregar CND (2022) The use of carrot seed oil (Daucus Carota L.) to formulate nanoemulgels as an effective natural sunscreen and skin anti-aging. Int J Appl Pharm 14(1):124–129. https://doi.org/10.22159/ijap.2022v14i1.43481

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