Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 May 28;24(1):367.
doi: 10.1186/s12887-024-04844-6.

IgE to wheat, prick test, and Patch test among children with celiac disease

Marjaneh Khalighi  1 , Hazhir Javaherizadeh  2 , Mehran Hakimzadeh  1 , Mitra Ahmadi  1 , Mehdi Torabizadeh  3 , Abbas Fayezi  3
Affiliations

IgE to wheat, prick test, and Patch test among children with celiac disease

Marjaneh Khalighi et al. BMC Pediatr. .

Abstract

Introduction and aim: Celiac disease is one of the most common autoimmune disorders. This study aimed to evaluate the relationship between celiac disease and wheat sensitization.

Subjects and methods: In the current study, children aged < 18 years with confirmed celiac disease were included. Data were analyzed using SPSS.

Results: Gastrointestinal problems were the most common indication for evaluation in terms of celiac disease. Prick and patch tests were positive in 43.4% and 34% respectively.

Conclusion: Prick test and patch test for wheat sensitization were positive in about 30-45% of the children for celiac disease.

Keywords: Celiac disease; Diarrhea; Patch test; Prick test.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

References

    1. Šťastná M, Norek A, Řádková J, Sluková M, Hrunka M, Jabandžiev P, et al. Increasing prevalence of celiac disease - where to look for answers? Epidemiol Mikrobiol Imunol. 2023;72(3):172–83. - PubMed
    1. Mennini M, Fiocchi A, Trovato CM, Ferrari F, Iorfida D, Cucchiara S, et al. Anaphylaxis after wheat ingestion in a patient with coeliac disease: two kinds of reactions and the same culprit food. Eur J Gastroenterol Hepatol. 2019;31(7):893–5. doi: 10.1097/meg.0000000000001421. - DOI - PubMed
    1. Martín-Muñoz MF, Rivero D, Díaz Perales A, Polanco I, Quirce S. Wheat allergy in celiac children. Pediatr Allergy Immunol. 2016;27(1):102–5. doi: 10.1111/pai.12487. - DOI - PubMed
    1. Corazza GR, Villanacci V. Coeliac disease. J Clin Pathol. 2005;58(6):573–4. doi: 10.1136/jcp.2004.023978. - DOI - PMC - PubMed
    1. Mansouri M, Rafiee E, Darougar S, Mesdaghi M, Chavoshzadeh Z. Is the Atopy Patch Test Reliable in the evaluation of Food Allergy-related atopic dermatitis? Int Arch Allergy Immunol. 2018;175(1–2):85–90. doi: 10.1159/000485126. - DOI - PubMed

Substances