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Case Reports
. 2024 Nov;90(11):3131-3133.
doi: 10.1177/00031348241257466. Epub 2024 May 28.

Incipient Intracholecystic Papillary Neoplasm of the Gallbladder Without Dysplasia

Joseph S Lim  1 , Alejandra Dominguez  2 , Nathaniel Kidd  2 , Kumaran Mudaliar  3 , Joseph F Buell  1 , Dhiresh Rohan Jeyarajah  1   2 , Houssam Osman  1
Affiliations
Case Reports

Incipient Intracholecystic Papillary Neoplasm of the Gallbladder Without Dysplasia

Joseph S Lim et al. Am Surg. 2024 Nov.

Abstract

Intracholecystic papillary neoplasm (ICPN) of the gallbladder is a rare tumor described as a mucosal exophytic neoplastic lesion that projects into the gallbladder lumen. In regards to the size, lesions that did not make the arbitrary 1cm cutoff are described as "incipient" ICPN. Not much is known about these incipient ICPNs, as they are often excluded in ICPN studies, given the attempted adherence to the traditional 1cm cutoff. We present the youngest reported case of incipient, non-mucinous gastric-pylorus type ICPN who underwent cholecystectomy. Resection with negative margin for ICPN appears to be sufficient treatment and post resection imaging surveillance could be of value but further studies are required.

Keywords: ICPN; gallbladder.

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Conflict of interest statement

Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Dr Jeyarajah is a consultant for AngioDynamics, Ethicon, and Sirtex.

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