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Review
. 2024 Jul;24(14):e2300522.
doi: 10.1002/pmic.202300522. Epub 2024 May 29.

Proteomics is advancing the understanding of stallion sperm biology

Fernando J Peña  1 , Francisco Eduardo Martín-Cano  1 , Laura Becerro-Rey  1 , Cristina Ortega-Ferrusola  1 , Gemma Gaitskell-Phillips  1 , Eva da Silva-Álvarez  1 , María Cruz Gil  1
Affiliations
Review

Proteomics is advancing the understanding of stallion sperm biology

Fernando J Peña et al. Proteomics. 2024 Jul.

Abstract

The mammalian ejaculate is very well suited to proteomics studies. As such, research concerning sperm proteomics is offering a huge amount of new information on the biology of spermatozoa. Among domestic animals, horses represent a species of special interest, in which reproductive technologies and a sizeable market of genetic material have grown exponentially in the last decade. Studies using proteomic approaches have been conducted in recent years, showing that proteomics is a potent tool to dig into the biology of the stallion spermatozoa. The aim of this review is to present an overview of the research conducted, and how these studies have improved our knowledge of stallion sperm biology. The main outcomes of the research conducted so far have been an improved knowledge of metabolism, and its importance in sperm functions, the impact of different technologies on the sperm proteome, and the identification of potential biomarkers. Moreover, proteomics of seminal plasma and phosphoproteomics are identified as areas of major interest.

Keywords: proteome; seminal plasma; spermatozoa; stallion.

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References

REFERENCES

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