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Review
. 2024 May 14:19:e04.
doi: 10.15420/ecr.2023.47. eCollection 2024.

Left Atrium: A New Prognostic Marker and Therapeutic Target in Secondary Mitral Regurgitation?

Markos Koukos  1 , Yannis Dimitroglou  1 , Dimitrios Tsartsalis  1 , Eirini Beneki  1 , Elias Tolis  1 , Dimitrios Patsourakos  1 , Argyro Kalompatsou  1 , Constantina Aggeli  1 , Konstantinos Tsioufis  1
Affiliations
Review

Left Atrium: A New Prognostic Marker and Therapeutic Target in Secondary Mitral Regurgitation?

Markos Koukos et al. Eur Cardiol. .

Abstract

Mitral regurgitation (MR) is one of the most common valvular abnormalities worldwide and can be subdivided into primary and secondary causes. Atrial MR consists of a novel type of secondary MR (SMR), most often observed in patients with AF and heart failure with preserved ejection fraction. The main pathophysiological mechanism of atrial MR is mitral valve annular dilatation. Recently published studies have highlighted the clinical significance of left atrium (LA) evaluation in the early diagnosis and prognosis of patients with primary MR. However, there are little data regarding the role of the LA in SMR. The present literature review aims to elucidate the use of the echocardiographic parameters regarding LA evaluation in the prognosis prediction and therapeutic strategy of patients with SMR.

Keywords: Secondary mitral regurgitation; left atrium; speckle tracking; strain.

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Conflict of interest statement

Disclosure: The authors have no conflicts of interest to declare.

Figures

Figure 1:
Figure 1:. Multimodality Imaging Delineating the Pathophysiologic Mechanisms of Secondary Mitral Regurgitation
Figure 2:
Figure 2:. Speckle Tracking Strain of the Left Atrium
See this image and copyright information in PMC

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