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Review
. 2025 Apr;72 Suppl 2(Suppl 2):e31118.
doi: 10.1002/pbc.31118. Epub 2024 May 29.

Current surgical approaches to pediatric renal tumors

Affiliations
Review

Current surgical approaches to pediatric renal tumors

Richard D Glick et al. Pediatr Blood Cancer. 2025 Apr.

Abstract

Pediatric renal tumors are among the most common pediatric solid malignancies. Surgical resection is a key component in the multidisciplinary therapy for children with kidney tumors. Therefore, it is imperative that surgeons caring for children with renal tumors fully understand the current standards of care in order to provide appropriate surgical expertise within this multimodal framework. Fortunately, the last 60 years of international, multidisciplinary pediatric cancer cooperative group studies have enabled high rates of cure for these patients. This review will highlight the international surgical approaches to pediatric patients with kidney cancer to help surgeons understand the key differences and similarities between the European (International Society of Pediatric Oncology) and North American (Children's Oncology Group) recommendations.

Keywords: Wilms tumor; kidney tumor; pediatric; renal cell carcinoma; renal tumor.

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References

    1. Ali AN, Diaz R, Shu HK, et al.: A Surveillance, Epidemiology and End Results (SEER) program comparison of adult and pediatric Wilms’ tumor. Cancer 2012; 118: 2541–2551. - PubMed
    1. Libes J, Hol J, Neto JCA, et al.: Pediatric renal tumor epidemiology: Global perspectives, progress, and challenges. Pediatr Blood Cancer 2023; 70 Suppl 2: e30343. - PubMed
    1. Nakata K, Colombet M, Stiller CA, et al.: Incidence of childhood renal tumours: An international population-based study. Int J Cancer 2020; 147: 3313–3327. - PMC - PubMed
    1. Ehrlich P, Chi YY, Chintagumpala MM, et al.: Results of the First Prospective Multi-institutional Treatment Study in Children With Bilateral Wilms Tumor (AREN0534): A Report From the Children’s Oncology Group. Ann Surg 2017; 266: 470–478. - PMC - PubMed
    1. Ehrlich PF, Chi YY, Chintagumpala MM, et al.: Results of Treatment for Patients With Multicentric or Bilaterally Predisposed Unilateral Wilms Tumor (AREN0534): A report from the Children’s Oncology Group. Cancer 2020; 126: 3516–3525. - PMC - PubMed

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