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Editorial
. 2024 Jul 5;147(7):2261-2263.
doi: 10.1093/brain/awae172.

Investigation of network reorganization after epilepsy surgery is worth the effort

Lucas E Sainburg  1   2 , Victoria L Morgan  1   2   3
Affiliations
Editorial

Investigation of network reorganization after epilepsy surgery is worth the effort

Lucas E Sainburg et al. Brain. .

Abstract

This scientific commentary refers to ‘Connectome reorganization associated with temporal lobe pathology and its surgical resection’ by Larivière et al. (https://doi.org/10.1093/brain/awae141).

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Conflict of interest statement

The authors report no competing interests.

Figures

Figure 1
Figure 1
Anatomic MRI (left), diffusion tractography (middle) and structural connectomes (right) acquired before and after right temporal lobectomy in a patient with unilateral temporal lobe epilepsy. Anatomical images highlight the resection cavity (yellow arrow) and brain shift (red arrow) after surgery. The lower structural connectome highlights both connectivity increases and decreases from pre- to post-surgery. Blue bars indicate removal of resected regions from the connectome. L = left; R = right.
See this image and copyright information in PMC

Comment on

References

    1. Larivière S, Bernasconi A, Bernasconi N, Bernhardt BC. Connectome biomarkers of drug-resistant epilepsy. Epilepsia. 2021;62:6–24. - PubMed
    1. Janson A, Sainburg L, Akbarian B, et al. Indirect structural changes and reduced controllability after temporal lobe epilepsy resection. Epilepsia. 2024;65:675–686. - PMC - PubMed
    1. Sainburg LE, Janson AP, Johnson GW, et al. Structural disconnection relates to functional changes after temporal lobe epilepsy surgery. Brain. 2023;146:3913–3922. - PMC - PubMed
    1. Larivière S, Park B-y, Royer J, et al. Connectome reorganization associated with temporal lobe pathology and its surgical resection. Brain. 2024;147:2483-2495. - PMC - PubMed
    1. Sotiropoulos SN, Zalesky A. Building connectomes using diffusion MRI: Why, how and but. NMR Biomed. 2019;32:e3752. - PMC - PubMed