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Review
. 2024 May 15:15:1346639.
doi: 10.3389/fmicb.2024.1346639. eCollection 2024.

Gut microbiota in cats with inflammatory bowel disease and low-grade intestinal T-cell lymphoma

Amandine Drut  1   2 , Héla Mkaouar  1 , Aicha Kriaa  1 , Vincent Mariaule  1 , Nizar Akermi  1 , Tristan Méric  1   2 , Odile Sénécat  2 , Emmanuelle Maguin  1 , Juan Hernandez  1   2 , Moez Rhimi  1
Affiliations
Review

Gut microbiota in cats with inflammatory bowel disease and low-grade intestinal T-cell lymphoma

Amandine Drut et al. Front Microbiol. .

Abstract

In cats and humans, several physiological and environmental factors have been shown to alter the gut microbiota of healthy individuals. Cats share several diseases with humans such as inflammatory bowel diseases and low-grade intestinal T-cell lymphoma. The physiopathology of these chronic enteropathies is poorly understood but may involve disequilibrium of the gut microbiota composition and disruption of normal microbiome activity profiles. These disorders are increasingly diagnosed in the feline species due to improved medicalization and easier access to endoscopy in veterinary practice. This review addresses the current data on the gut microbiota of cats in health and in chronic enteropathies. Such functional analysis will help the advancement of innovative diagnostic tools and targeted therapeutic strategies.

Keywords: cat; chronic enteropathies; gut microbiota; inflammatory bowel diseases; low-grade intestinal T-cell lymphoma.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Overview of major changes in the gut microbiota composition and activities in cats with chronic enteropathies (inflammatory bowel diseases and low-grade intestinal T-cell lymphoma). Up and down arrows represent increases and decreases, respectively. BA, bile acids; IBD, inflammatory bowel diseases; LGITL, low-grade intestinal T-cell lymphoma; PUFA, polyunsaturated fatty acid.
See this image and copyright information in PMC

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