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Editorial
. 2024 May 7;30(17):2308-2310.
doi: 10.3748/wjg.v30.i17.2308.

Chronic active and atrophic gastritis as significant contributing factor to the development of gastric cystica profunda

Veronika Papp  1 , Pál Miheller  2
Affiliations
Editorial

Chronic active and atrophic gastritis as significant contributing factor to the development of gastric cystica profunda

Veronika Papp et al. World J Gastroenterol. .

Abstract

Gastric cystica profunda (GCP) is an uncommon but underestimated gastric lesion. Its precancerous potential determines its significance. In addition to previous mucosa injury due to operations, biopsy or polypectomy, chronic active and atrophic gastritis may also lead to the development of GCPs. By carefully examining the stomach and taking biopsy samples from the susceptible regions, the stage of atrophy can be determined. Chronic atrophic gastritis is a risk factor for cancer evolvement and it can also contribute to GCPs formation. GCPs frequently occur close to early gastric cancers (EGCs) or EGC can arise from the cystic glands. Endoscopic resection is an effective and minimally invasive treatment in GCP.

Keywords: Atrophic gastritis; Chronic active gastritis; Early gastric cancer; Endoscopic resection; Gastric cystica profunda; Operative Link for Gastritis Assessment staging.

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Conflict of interest statement

Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.

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