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. 2024 Oct 1;109(10):3435-3438.
doi: 10.3324/haematol.2024.285612.

Infrequent fractures and resilient bone mineral density: bone health in patients with Fanconi anemia

Jane Koo  1 , Jonathan C Howell  2 , Lindsey Hornung  3 , Anthony Sabulski  4 , Parinda A Mehta  4 , Stella M Davies  4 , Kasiani C Myers  4
Affiliations

Infrequent fractures and resilient bone mineral density: bone health in patients with Fanconi anemia

Jane Koo et al. Haematologica. .
No abstract available

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Figures

Figure 1.
Figure 1.
Longitudinal changes in bone mineral density in hematopoietic stem cell transplant and non- hematopoietic stem cell transplant patients with Fanconi anemia. Shown are the longitudinal changes in lumbar spine height-adjusted (adj) bone mineral density Z-scores (HAZ) in patients who received hematopoietic stem cell transplant (HSCT) with respect to time of HSCT (time 0). The grey zone spanning from bone mineral density (BMD) Z-scores between -2 and 2 represent normal BMD Z-scores. Each individual green line represents a single patient over time with each circle representing each time a dual energy x-ray absorptiometry (DXA) scan was completed. The overall linear regression analysis of all patients are represented by the bold black line. (A) Regression analysis demonstrated a β coefficient of -0.02 over time in HSCT recipients (P=0.49). (B) Regression analysis also demonstrated a stable β coefficient of 0.004 in non-HSCT recipients over time with age (P=0.95).
See this image and copyright information in PMC

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