doi: 10.1128/jb.161.2.767-768.1985.
Identity of the photoproduct that causes lacI mutations in UV-irradiated Escherichia coli
- PMID: 3881409
- PMCID: PMC214949
- DOI: 10.1128/jb.161.2.767-768.1985
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Identity of the photoproduct that causes lacI mutations in UV-irradiated Escherichia coli
J Bacteriol.
1985 Feb.
Abstract
Estimates of the capacity of photoreactivation to act specifically on premutational lesions were obtained by conjugational transfer of an F' lac plasmid from a UV-irradiated, photoreactivated donor to a delta (pro-lac) recipient that had been UV irradiated and allowed to induce SOS functions for 30 min. This treatment reduced the frequency of induced lacI mutations by 70 to 80%, indicating that cyclobutane dimers cause most mutations in this system.
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