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. 2024 May 1;7(5):e2412870.
doi: 10.1001/jamanetworkopen.2024.12870.

Young-Onset Dementia Among Individuals With History of Preeclampsia

Valérie Olié  1 , Grégory Lailler  1   2 , Marion J Torres  1 , Nolwenn Regnault  1 , Laure Carcaillon-Bentata  3 , Jacques Blacher  4
Affiliations

Young-Onset Dementia Among Individuals With History of Preeclampsia

Valérie Olié et al. JAMA Netw Open. .
No abstract available

Plain language summary

This cohort study assesses the risk of developing early-onset dementia in individuals who had preeclampsia and other hypertensive disorders during pregnancy.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Blacher reported receiving personal fees from Abbott, Amgen, Astellas, Astra-Zeneca, Bayer, BMS, Boehringer Ingelheim, Bouchara-Recordati, Daiichi Sankyo, ElKendi, Ferring, Gilead, Hikma, Icomed, Leurquin, MSD, Novo Nordisk, Omron, Organon, Quantum Genomics, Sanofi Aventis, Saint Jude, Vivactis, and Vivoptim outside the submitted work. No other disclosures were reported.

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References

    1. Chappell LC, Cluver CA, Kingdom J, Tong S. Pre-eclampsia. Lancet. 2021;398(10297):341-354. doi:10.1016/S0140-6736(20)32335-7 - DOI - PubMed
    1. Schliep KC, Mclean H, Yan B, et al. . Association between hypertensive disorders of pregnancy and dementia: a systematic review and meta-analysis. Hypertension. 2023;80(2):257-267. doi:10.1161/HYPERTENSIONAHA.122.19399 - DOI - PMC - PubMed
    1. Boucheron P, Lailler G, Moutengou E, et al. . Hypertensive disorders of pregnancy and onset of chronic hypertension in France: the nationwide CONCEPTION study. Eur Heart J. 2022;43(35):3352-3361. doi:10.1093/eurheartj/ehab686 - DOI - PubMed
    1. Schliep KC, Shaaban CE, Meeks H, et al. . Hypertensive disorders of pregnancy and subsequent risk of Alzheimer’s disease and other dementias. Alzheimers Dement (Amst). 2023;15(2):e12443. doi:10.1002/dad2.12443 - DOI - PMC - PubMed
    1. Beckett AG, McFadden MD, Warrington JP. Preeclampsia history and postpartum risk of cerebrovascular disease and cognitive impairment: potential mechanisms. Front Physiol. 2023;14:1141002. doi:10.3389/fphys.2023.1141002 - DOI - PMC - PubMed

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