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. 2024 Sep:272:114121.
doi: 10.1016/j.jpeds.2024.114121. Epub 2024 May 28.

Child Opportunity Index Mobility, Recurrent Wheezing, and Asthma in Early Childhood: A Population-Based Prospective Cohort Study

Jordan Tyris  1 , Diane L Putnick  2 , Erin M Bell  3 , Jordan McAdam  4 , Tzu-Chun Lin  5 , Kavita Parikh  6 , Edwina Yeung  2
Affiliations

Child Opportunity Index Mobility, Recurrent Wheezing, and Asthma in Early Childhood: A Population-Based Prospective Cohort Study

Jordan Tyris et al. J Pediatr. 2024 Sep.

Abstract

We prospectively examined associations between mobility in neighborhood opportunity and early childhood recurrent wheezing/asthma. Downward mobility was associated with developing asthma, but not recurrent wheezing, though associations were attenuated after adjusting for family-level socioeconomic status. Elucidating how neighborhoods impact asthma may inform asthma equity initiatives in early childhood.

Keywords: asthma; epidemiology; health equity; recurrent wheeze; social determinants of health.

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Conflict of interest statement

Declaration of Competing Interest This work was supported by the Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD contractsHHSN275201200005C,HHSN267200700019C). J.T. was supported by the NICHD through the Pediatric Scientist Development Program. The Pediatric Scientist Development Program is supported by Award Number K12-HD000850 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and partnering organizations including the American Academy of Pediatrics, American Pediatric Society, Burroughs Wellcome Fund, Cystic Fibrosis Foundation, and the March of Dimes. K.P. reports funding from grant numbers 1R03HS028484-01A1 from the Agency for Healthcare Research and Quality, 1R01HL161665-01 from the NIH/NHLBI, and 1R25HD111358 from the NIH/NICHD. The other authors declare no conflicts of interest.

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