Carrier testing for partners of MUTYH variant carriers: UK Cancer Genetics Group recommendations

Terri Patricia McVeigh^{1

2}, Fiona Lalloo³, Kevin J Monahan^{4

5}, Andrew Latchford^{6

7}, Miranda Durkie⁸, Rachael Mein⁹, Emma L Baple^{10

11}, Helen Hanson^{11

12}

Affiliations

¹ Cancer Genetics Unit, Royal Marsden Hospital NHS Foundation Trust, London, UK terri.mcveigh@gmail.com.
² The Institute of Cancer Research, London, UK.
³ Manchester Centre for Genomic Medicine, Manchester University Hospitals Foundation Trust, Manchester, UK.
⁴ St Mark's the National Bowel Hospital and Academic Institute, London, UK.
⁵ Imperial College London, London, UK.
⁶ The Polyposis Registry, St Mark's Centre for Familial Intestinal Cancer, St Mark's Hospital, London, UK.
⁷ Surgery and Cancer, Imperial College London, London, UK.
⁸ Sheffield Diagnostic Genetics Service, North East and Yorkshire Genomic Laboratory Hub, Sheffield Children's NHS Foundation Trust, Sheffield, UK.
⁹ NHS England, Redditch, UK.
¹⁰ Medical Research (Level 4), RILD Wellcome Wolfson Centre, University of Exeter, Exeter, UK.
¹¹ Peninsula Clinical Genetics Service, Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK.
¹² Faculty of Health and Life Sciences, University of Exeter Medical School, Exeter, UK.

Terri Patricia McVeigh et al. J Med Genet. 2024.

. 2024 Jul 19;61(8):813-816.

doi: 10.1136/jmg-2024-109910.

Terri Patricia McVeigh^{1

2}, Fiona Lalloo³, Kevin J Monahan^{4

5}, Andrew Latchford^{6

7}, Miranda Durkie⁸, Rachael Mein⁹, Emma L Baple^{10

11}, Helen Hanson^{11

12}

¹ Cancer Genetics Unit, Royal Marsden Hospital NHS Foundation Trust, London, UK terri.mcveigh@gmail.com.
² The Institute of Cancer Research, London, UK.
³ Manchester Centre for Genomic Medicine, Manchester University Hospitals Foundation Trust, Manchester, UK.
⁴ St Mark's the National Bowel Hospital and Academic Institute, London, UK.
⁵ Imperial College London, London, UK.
⁶ The Polyposis Registry, St Mark's Centre for Familial Intestinal Cancer, St Mark's Hospital, London, UK.
⁷ Surgery and Cancer, Imperial College London, London, UK.
⁸ Sheffield Diagnostic Genetics Service, North East and Yorkshire Genomic Laboratory Hub, Sheffield Children's NHS Foundation Trust, Sheffield, UK.
⁹ NHS England, Redditch, UK.
¹⁰ Medical Research (Level 4), RILD Wellcome Wolfson Centre, University of Exeter, Exeter, UK.
¹¹ Peninsula Clinical Genetics Service, Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK.
¹² Faculty of Health and Life Sciences, University of Exeter Medical School, Exeter, UK.

No abstract available

Keywords: DNA Repair; Delivery of Health Care; Digestive System Neoplasms; Gastroenterology; Genetic Carrier Screening.

Conflict of interest statement

Competing interests: None declared.

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