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. 2024 Jan-Feb;39(1):63-65.
doi: 10.4103/ijnm.ijnm_130_23. Epub 2024 Mar 27.

Primary Leiomyosarcoma of Suprahepatic Inferior Vena Cava with Metastases

Anitha Mandava  1 , Veeraiah Koppula  1 , Meghana Kandati  1 , Arvind Kumar Reddy  1 , Zakir Ali Abubacker  2
Affiliations

Primary Leiomyosarcoma of Suprahepatic Inferior Vena Cava with Metastases

Anitha Mandava et al. Indian J Nucl Med. 2024 Jan-Feb.

Abstract

A 67-year-old female presented with shortness of breath, weight loss, abdomen, and back pain for 2 months. Ultrasound of the abdomen revealed multiple focal liver lesions. 18F-Fluorodeoxyglucose whole-body positron emission tomography/computed tomography revealed a hypermetabolic lesion in the suprahepatic inferior vena cava extending into the right atrium. Multiple hypermetabolic lesions were seen in liver, bones, and abdominal lymph nodes, suggestive of metastases. Histopathology and immunohistochemistry of the lesions revealed it to be metastatic leiomyosarcoma.

Keywords: Inferior vena cava; leiomyosarcoma; metastases; positron emission tomography/computed tomography; right atrium.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a-d) Axial contrast-enhanced computed tomography and corresponding positron emission tomography/computed tomography (PET/CT) fusion images of chest and abdomen show mildly enhancing hypoattenuating hypermetabolic lesion in the inferior cavoatrial junction (thick arrows), metastases in liver (arrows), and enlarged precaval lymph node (elbow arrows). (e and f) Axial PET/CT fusion images of the neck and pelvis show bone metastases in vertebral body and left iliac bone (arrows).
Figure 2
Figure 2
(a-c) Sagittal whole-body computed tomography (CT) and positron emission tomography/CT fusion images show hypermetabolic lesion in the suprahepatic inferior vena cava and right atrium (thick arrow), metastases in liver (arrows) and spine (arrow heads)
Figure 3
Figure 3
H and E × 40: Round to ovoid tumor cells with eosinophilic granular cytoplasm and irregularly shaped nuclei of leiomyosarcoma
See this image and copyright information in PMC

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