Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 May 30;12(5):e5809.
doi: 10.1097/GOX.0000000000005809. eCollection 2024 May.

Outcomes of Mastectomy and Immediate Reconstruction Managed with Closed-incision Negative Pressure Therapy Applied Over the Whole Breast

Allen Gabriel  1   2 , Vivian Chan  2
Affiliations

Outcomes of Mastectomy and Immediate Reconstruction Managed with Closed-incision Negative Pressure Therapy Applied Over the Whole Breast

Allen Gabriel et al. Plast Reconstr Surg Glob Open. .

Abstract

Background: Incision healing after mastectomy and immediate reconstruction can be supported with closed-incision negative pressure therapy (ciNPT). Studies have reported patients receiving postoperative care with ciNPT after breast surgery exhibited lower rates of dehiscence, infection, necrosis, and seroma, compared with standard dressings. A recent approach to ciNPT involves the application of negative pressure to the incision and a wider area of surrounding tissue. In this retrospective review, we investigated the outcomes of ciNPT using full-coverage dressings over the entire breast after mastectomy and reconstruction.

Methods: Patients underwent mastectomies and immediate prepectoral breast reconstruction with an implant or tissue expander. After surgery, patients received oral antibiotics and ciNPT with full-coverage foam dressings at -125 mm Hg.

Results: All 54 patients (N = 105 incisions) were women, with a mean age of 53.5 years and 29.1 kg per m2 body mass index. Common comorbidities included prior chemotherapy (31.3%) or radiation (21.6%), hypertension (14.8%), and diabetes (5.6%). Procedures included skin-reducing (34.3%), skin-sparing (7.6%), and nipple-sparing (58.1%) mastectomies. Lymph nodes were removed in 38 (36.2%) incisions. All patients were discharged home with ciNPT on postoperative day (POD) 1, and ciNPT was discontinued on POD 5-7. At POD 30, three patients developed seromas, requiring revision. Of these, one required removal of the left tissue expander. The remaining 102 incisions (97.1%) healed without complication.

Conclusions: Among this cohort, the use of ciNPT with full-dressing coverage of the breast incisions and surrounding soft tissue was effective in supporting incisional healing after mastectomy and immediate reconstruction.

PubMed Disclaimer

Conflict of interest statement

Dr. Gabriel is a consultant of 3M Company (San Antonio, Tex.) and a consultant for Allergan. Dr. Chan has nothing to disclose.

Figures

Fig. 1.
Fig. 1.
Breast appearance premastectomy.
Fig. 2.
Fig. 2.
Application of ciNPT with full-coverage foam dressings post mastectomy.
Fig. 3.
Fig. 3.
Appearance on postoperative day 7, immediately after removal of ciNPT dressings.
Fig. 4.
Fig. 4.
Appearance 1 year post mastectomy, after exchange to silicone implants. Results are viewed from the right (A), center (B), and left (C).
Fig. 5.
Fig. 5.
Breast appearance premastectomy.
Fig. 6.
Fig. 6.
Application of ciNPT with full-coverage foam dressings post mastectomy.
Fig. 7.
Fig. 7.
Appearance after 7 days of ciNPT, immediately after removal of dressings.
Fig. 8.
Fig. 8.
Appearance 9 months post mastectomy, after exchange to silicone implants. Results are viewed from the right (A), center (B), and left (C).
See this image and copyright information in PMC

References

    1. American Society of Plastic Surgeons. 2018 National Plastic Surgery Statistics report. Available at https://www.plasticsurgery.org/documents/News/Statistics/2018/plastic-su.... 2019. Accessed May 15, 2024.
    1. Yoon AP, Qi J, Brown DL, et al. Outcomes of immediate versus delayed breast reconstruction: results of a multicenter prospective study. Breast. 2018;37:72–79. - PMC - PubMed
    1. Gabriel A, Sigalove S, Sigalove N, et al. The impact of closed incision negative pressure therapy on postoperative breast reconstruction outcomes. Plast Reconstr Surgery Global Open. 2018;6:e1880. - PMC - PubMed
    1. Ferrando PM, Ala A, Bussone R, et al. Closed incision negative pressure therapy in oncological breast surgery: comparison with standard care dressings. Plast Reconstr Surgery Global Open. 2018;6:e1732. - PMC - PubMed
    1. Muller-Sloof E, de Laat HE, Hummelink SL, et al. The effect of postoperative closed incision negative pressure therapy on the incidence of donor site wound dehiscence in breast reconstruction patients: DEhiscence PREvention Study (DEPRES), pilot randomized controlled trial. J Tissue Viability. 2018;27:262–266. - PubMed