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. 2024 Jul 1;27(4):447-449.
doi: 10.4103/aian.aian_28_24. Epub 2024 Apr 19.

Polyneuropathy Unveiling a Hidden Hepatic Plasmacytoma: An Extremely Rare Association

Archita Makharia  1 , Ayush Agarwal  1 , Divyani Garg  1 , Shamim A Shamim  2 , Rajni Yadav  3 , Priyanka Mani  3 , Divya M Radhakrishnan  1 , Awadh K Pandit  1 , Achal K Srivastava  1
Affiliations

Polyneuropathy Unveiling a Hidden Hepatic Plasmacytoma: An Extremely Rare Association

Archita Makharia et al. Ann Indian Acad Neurol. .
No abstract available

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) FDG MIP image shows focal area of increased metabolism in the liver and abdominal lymph nodes. (b, c) Fused axial and coronal PET/CT images show an FDG-avid mass arising from the gall bladder and infiltrating into adjacent segments V/VIII of the liver (green arrow). (d, e) Fused axial PET/CT image shows FDG-avid, enlarged periportal, precaval, and paracaval lymph nodes (gray arrow). CT = computed tomography, FDG = fluorodeoxyglucose, MIP = maximum intensity projection, PET = positron emission tomography
Figure 2
Figure 2
(a) Sections examined from liver biopsy show cores of liver tissue with sheets of atypical cells, 100× (H and E). (b) The atypical cells are round and contain moderate amount of eosinophilic cytoplasm and eccentrically placed nuclei, 400× (H and E). (c, d) These cells are immunopositive for CD138 and MUM1, 400× (IHC). (e, f) The cells are negative for kappa, while they are positive for lambda, 200× (IHC). H and E = hematoxylin and eosin, IHC = immunohistochemistry
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References

    1. Huang H, Bazerbachi F, Mesa H, Gupta P. Asymptomatic multiple myeloma presenting as a nodular hepatic lesion: A case report and review of the literature. Ochsner J. 2015;15:457–67. - PMC - PubMed
    1. Dimopoulos MA, Hamilos G. Solitary bone plasmacytoma and extramedullary plasmacytoma. Curr Treat Options Oncol. 2002;3:255–9. - PubMed
    1. Husaric S, Pasic J, Alic E, Kuljanin M. Solitary extramedullary plasmacytoma of the liver. Acta Med Acad. 2013;42:85–6. - PubMed
    1. Bladé J, Fernández de Larrea C, Rosiñol L, Cibeira MT, Jiménez R, Powles R. Soft-tissue plasmacytomas in multiple myeloma: Incidence, mechanisms of extramedullary spread, and treatment approach. J Clin Oncol. 2011;29:3805–12. - PubMed
    1. Finsinger P, Grammatico S, Chisini M, Piciocchi A, Foà R, Petrucci MT. Clinical features and prognostic factors in solitary plasmacytoma. Br J Haematol. 2016;172:554–60. - PubMed