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Case Reports
. 2024 Sep;40(9):2957-2960.
doi: 10.1007/s00381-024-06471-z. Epub 2024 May 31.

Vasospasm and subsequent stroke from paraneoplastic syndrome in a pediatric patient with an intracranial mature teratoma: a case report

Amanda V Jenson  1 , Ali Yunus Rizvi  2 , Rebecca A Reynolds  3 , Sara Hartnett-Wright  4 , Thomas J Gellar  5 , Stacie Stapleton  6 , Ignacio Gonzalez-Gomez  7 , S Hassan A Akbari  4 , Matthew D Smyth  4
Affiliations
Case Reports

Vasospasm and subsequent stroke from paraneoplastic syndrome in a pediatric patient with an intracranial mature teratoma: a case report

Amanda V Jenson et al. Childs Nerv Syst. 2024 Sep.

Abstract

Teratomas account for 18-20% of all intracranial germ cell tumors and mostly occur in the pineal region with only a few cases of pediatric sellar and suprasellar teratomas described in the literature. Here, we present a case of a child with an intracranial mature teratoma with pancreatic features causing vasospasm and subsequent stroke, found to be positive for CDKN2A-an independent variant associated with malignancy and small vessel disease leading to stroke.

Keywords: Intracranial teratoma; Paraneoplastic syndrome; Vasospasm.

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