Reducing seizures with senolytic drugs

Comment

Sarah Crunkhorn. Nat Rev Drug Discov. 2024 Jul.

. 2024 Jul;23(7):499.

doi: 10.1038/d41573-024-00092-6.

No abstract available

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Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy.
Ribierre T, Bacq A, Donneger F, Doladilhe M, Maletic M, Roussel D, Le Roux I, Chassoux F, Devaux B, Adle-Biassette H, Ferrand-Sorbets S, Dorfmüller G, Chipaux M, Baldassari S, Poncer JC, Baulac S. Ribierre T, et al. Nat Neurosci. 2024 Jun;27(6):1125-1136. doi: 10.1038/s41593-024-01634-2. Epub 2024 May 6. Nat Neurosci. 2024. PMID: 38710875 Free PMC article.

1. Ribierre, T. et al. Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy. Nat. Neurosci. https://doi.org/10.1038/s41593-024-01634-2 (2024)