Review
doi: 10.1007/BF00404859.
Why are enzymes macromolecules?
- PMID: 388239
- DOI: 10.1007/BF00404859
Item in Clipboard
Review
Why are enzymes macromolecules?
Naturwissenschaften.
1979 Oct.
Abstract
The possible reasons for the macromolecular nature of enzymes are discussed. They are recognized in the necessity of creating a highly specific stereochemistry and microenvironment in the active site, in the necessity of maintaining the protein conformational rigidity, its fit with the physiological environment and overall stability, in allostery, and in the possible existence of fossil sequences, molecular tinkering, and specific hydrodynamic properties.
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