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. 2024 Aug;71(8):e31120.
doi: 10.1002/pbc.31120. Epub 2024 Jun 2.

Cancer is not a risk factor for severe COVID-19 in children, except in patients with recent allogeneic hematopoietic stem cell transplantation or comorbidities

Pablo Velasco Puyó  1 , Alfredo Tagarro  2   3   4 , Susana Garcia-Obregon  5   6 , Olatz Villate  5 , Cinta Moraleda  2   7 , Jorge Huerta Aragonés  8   9   10 , Eduardo J Bardón Cancho  8   9   10 , Anna Faura Morros  11 , Víctor Galán-Gómez  12 , Laura Escobar Fernández  13 , Francisco Lendinez-Molinos  14 , Blanca Herrero Velasco  15 , Laura Ureña Horno  16 , Nerea Domínguez-Pinilla  17   18 , Juan Francisco Pascual Gazquez  19 , Cristina Nova Lozano  20 , Marta Osuna-Marco  21 , Inés Marín-Cruz  22   23 , Irene Gomez Pastrana  7 , Nagore Garcia de Andoin Barandiaran  24   25   26 , Nerea Gallego Mingo  27 , Raquel Portugal Rodríguez  28 , Adela Cañete  29 , Marta Pareja León  30 , Sara Castrillo Bustamante  31 , María Tallón García  32 , Almudena Gónzalez-Prieto  33 , María Solé-Rodríguez  34 , Macarena González Cruz  35 , Antonio Soriano-Arandes  36 , Miriam Mota  37 , Santiago Pérez-Hoyos  37 , Lucas Moreno  1 , Itziar Astigarraga  5   38   39 ; EPICO‐AEP Working Group
Affiliations

Cancer is not a risk factor for severe COVID-19 in children, except in patients with recent allogeneic hematopoietic stem cell transplantation or comorbidities

Pablo Velasco Puyó et al. Pediatr Blood Cancer. 2024 Aug.

Abstract

The EPICO (Spanish general registry of COVID-19 in children)-SEHOP (Spanish Society of Pediatric Hematology and Oncology) platform gathers data from children with SARS-CoV-2 in Spain, allowing comparison between children with cancer or allogeneic hematopoietic stem cell transplantation (alloHSCT) and those without. The infection is milder in the cancer/alloHSCT group than in children without comorbidities (7.1% vs. 14.7%), except in children with recent alloHSCT (less than 300 days), of which 35.7% experienced severe COVID-19. These data have been shared with the SEHOP members to support treatment and isolation policies akin to those for children without cancer, except for those with recent alloHSCT or additional comorbidities. This highlights the collaborative registries potential in managing pandemic emergencies.

Keywords: COVID‐19; Registry; allogenic HSCT; cancer; children; comorbidities.

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References

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