doi: 10.3760/cma.j.cn112151-20231025-00305.
[Genetic characteristics of ovarian malignant germ cell tumors]
[Article in
Chinese]
Affiliations
- PMID: 38825917
- DOI: 10.3760/cma.j.cn112151-20231025-00305
Item in Clipboard
[Genetic characteristics of ovarian malignant germ cell tumors]
[Article in
Chinese]
Zhonghua Bing Li Xue Za Zhi.
.
Abstract
卵巢恶性生殖细胞肿瘤主要受累人群为青少年、对国家人口政策和生育健康具有重要意义。卵巢恶性生殖细胞起源于发育异常、未凋亡的生殖细胞，目前，其病理学分型主要依据形态学进行分类，尚未纳入起源细胞的遗传学事件。依据对女性生殖细胞发育历程的新认识，本文将通过全面介绍和对比卵巢、睾丸及儿童生殖细胞肿瘤的研究进展，以期更加深入了解较为常见的几种卵巢恶性生殖细胞肿瘤的遗传学特征，进而辅助理解各亚型普通谱系分化的原因以及寻找用于临床诊断、监测的潜在靶点。.
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