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Case Reports
. 2024 May 31;2024(5):rjae352.
doi: 10.1093/jscr/rjae352. eCollection 2024 May.

Rare adrenal incidentaloma: ganglioneuroma

Yassine Daghdagh  1 , Reda Safwate  1 , Abderrahmane Doumer  1 , Amine Moataz  1 , Mohamed Dakir  1 , Adil Debbagh  1 , Rachid Aboutaieb  1 , Abd Mellouki  2 , Samira Benayad  2 , Mehdi Karkouri  2
Affiliations
Case Reports

Rare adrenal incidentaloma: ganglioneuroma

Yassine Daghdagh et al. J Surg Case Rep. .

Abstract

Ganglioneuroma (GN) is a rare, benign neurogenic tumor that develops from sympathetic ganglion cells. It occurs mainly in the retroperitoneal region. Adrenal localization is rare. We report a case of adrenal ganglioneuroma in a 22-year-old woman with no previous history of the disease. The tumor was discovered incidentally on an entero scan ordered as part of the etiological assessment for chronic diarrhea. The diagnosis was confirmed by pathological examination.

Keywords: ganglioneuroma; oncology; retroperitoneal tumor; urology.

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Conflict of interest statement

None declared. The examination of the patient was conducted in accordance with the Declaration of Helsinki Principles. Written informed consent was obtained from the patient for publication of this article.

Figures

Figure 1
Figure 1
Large right retroperitoneal mass, hypodense, oval, well defined, with regular contours (arrow: aorta; arrowhead: IVC).
Figure 2
Figure 2
MRI, well-limited oval right adrenal mass, slightly heterogeneous mixed T2 signal (arrow: aorta; arrowhead: compressed IVC).
Figure 3
Figure 3
MRI, voluminous lesion of the right adrenal medulla in hyposignal T1.
Figure 4
Figure 4
Adrenal piece, 14 × 13 × 9 cm3, 860 g, smooth, encapsulated surface
Figure 5
Figure 5
Histological images of our patient’s GN, showing a fusocellular proliferation of Schwanian-type cells with the presence of mature ganglion cells, isolated or grouped in piles (arrow). The stroma is fibrous and myxoid (Photo A: under standard coloration, enlargement x100) (Photo B: under standard coloration, enlargement x200).
See this image and copyright information in PMC

References

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