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Review
. 2024 May;40(Suppl 1):93-99.
doi: 10.1007/s12055-024-01736-3. Epub 2024 May 20.

Aortic valve replacement with rapid-deployment bioprosthesis in case of infective endocarditis: a literature review

Affiliations
Review

Aortic valve replacement with rapid-deployment bioprosthesis in case of infective endocarditis: a literature review

Antonio Piperata et al. Indian J Thorac Cardiovasc Surg. 2024 May.

Abstract

Purpose: Recently, the use of rapid deployment (RD) aortic valve prostheses has been introduced for the treatment of aortic valve replacement (AVR), showing excellent hemodynamic performances.According to these data, some groups have proposed new RD valves as an alternative solution in the case of infective aortic endocarditis (IAE) to reduce the use of foreign materials, and the manipulation of the annulus.The aim of this review is to report the results of early clinical experiences with the use of RD bioprostheses in the case of IAE, in order to discuss technical and clinical aspects of this emerging strategy to better elucidate its advantages and limitations as a potential therapeutic solution.

Methods: An in-depth search of PubMed from January to March 2023 was performed. English-language articles were selected independently by authors following the criteria in order to consider all available experiences (full papers, case reports, and case series) that have investigated the use of RD in case of IAE.

Results: The use of rapid deployment bioprosthesis represents a bailout strategy in case of severe aortic valve endocarditis and should be evaluated with caution in selected cases. This review collects the first, initial, and pioneering experiences of the use of the RD prosthesis in case of infective endocarditis, particularly when the fragility of the annular tissues precludes a secure anchoring of sutured prostheses.The reduced use of foreign materials by minimizing the number of stitches, the reduced cardiopulmonary bypass (CPB) and aortic cross-clamp times, and the excellent hemodynamic performances associated with the use of RD bioprosthesis represent the most important advantages that could justify their use in the setting of aortic valve endocarditis.

Conclusion: Although there are few anecdotal experiences, surgical aortic valve replacement with the use of RD represents an emerging strategy in case of aortic valve endocarditis. Its advantages, pros, and cons are under debate, and robust clinical trials are needed to demonstrate its safety and efficacy.

Keywords: Aortic valve; Cardiac surgery; Infective endocarditis.

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Conflict of interest statement

Conflict of interestThe author does not have any conflict of interest to declare.

Figures

Fig. 1
Fig. 1
The flowchart of the study

References

    1. Delgado V, Ajmone Marsan N, de Waha S, Bonaros N, Brida M, Burri H, et al. ESC Scientific Document Group. 2023 ESC Guidelines for the management of endocarditis. Eur Heart J. 2023;44:3948–4042. doi: 10.1093/eurheartj/ehad193. - DOI - PubMed
    1. Cahill TJ, Prendergast BD. Infective endocarditis. Lancet. 2016;387(10021):882–93. doi: 10.1016/S0140-6736(15)00067-7. - DOI - PubMed
    1. Kang DH, Kim YJ, Kim SH, Sun BJ, Kim DH, Yun SC, et al. Early surgery versus conventional treatment for infective endocarditis. N. Engl. J. Med. 2012;366:2466–2473. doi: 10.1056/NEJMoa1112843. - DOI - PubMed
    1. Kang DH, Lee S, Kim YJ, Kim SH, Kim DH, Yun SC, et al. Long-term results of early surgery versus conventional treatment for Infective Endocarditis Trial. Korean Circ. J. 2016;46:846. doi: 10.4070/kcj.2016.46.6.846. - DOI - PMC - PubMed
    1. Öner A, Hemmer C, Alozie A, Löser B, Dohmen PM. Introduction of the rapid deployment aortic valve system use in elderly patients with endocarditis. Front Cardiovasc Med. 2022;22:774189. doi: 10.3389/fcvm.2022.774189. - DOI - PMC - PubMed

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