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Review
. 2024 Jul;53(7):503-510.
doi: 10.1007/s00132-024-04517-3. Epub 2024 Jun 3.

[Tissue biomechanics: connective tissue characterization : Cluster tissue biomechanics]

[Article in German]
Andreas Martin Seitz  1 , Anja Niehoff  2   3
Affiliations
Review

[Tissue biomechanics: connective tissue characterization : Cluster tissue biomechanics]

[Article in German]
Andreas Martin Seitz et al. Orthopadie (Heidelb). 2024 Jul.

Abstract
in English, German

The various connective tissues of the body have different functions, which result from their specific structure and composition. The identification of this structure-function relationship is of great importance for various disciplines such as medicine, biology or tissue engineering. Connective tissue consists mainly of an extracellular matrix (ECM) and a limited number of cells. It is extremely adaptable because the activity of the cells remodels the composition and structure of the ECM in order to adapt the mechanical properties (functions) to the new demands (e.g. an increased mechanical stimulus).

Die verschiedenen Bindegewebe des Körpers besitzen unterschiedliche Funktionen, die sich aus ihrer speziellen Struktur und Zusammensetzung ergeben. Die Identifizierung dieser Form-Funktions-Beziehung ist für unterschiedliche Disziplinen wie z. B. die Medizin, die Biologie oder das Tissue Engineering von hoher Bedeutung. Bindegewebe besteht hauptsächlich aus einer extrazellulären Matrix (ECM) und einer begrenzten Anzahl von Zellen. Es ist extrem anpassungsfähig, indem sich die Zusammensetzung und Struktur der ECM durch die Aktivität der Zellen verändert, um so die mechanischen Eigenschaften (Funktionen) an die neuen Anforderungen (z. B. vermehrte mechanische Belastung) zu adaptieren.

Keywords: Extracellular matrix; Materials testing; Mechanical processes; Structure-function relationship; Tissue engineering.

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References

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