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Editorial
. 2024 Jun 4;149(23):1830-1832.
doi: 10.1161/CIRCULATIONAHA.124.068657. Epub 2024 Jun 3.

Seeing is Believing: Muscleblind-like 1 Is Necessary For Mammalian Cardiomyocyte Maturation

Khalid B Dar  1 , Shah R Ali  1
Affiliations
Editorial

Seeing is Believing: Muscleblind-like 1 Is Necessary For Mammalian Cardiomyocyte Maturation

Khalid B Dar et al. Circulation. .
No abstract available

Keywords: Editorials; MBNL1 protein, human; RNA splicing; myocytes, cardiac; regeneration.

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Conflict of interest statement

Disclosures None.

Figures

Figure:
Figure:
NFATc and Hoxb13 are dephosphorylated by calcineurin to promote expression of Mbnl1 (Hoxb13 acts via its transcription factor binding partner, Meis1). Mbnl1 protein stabilizes spliced transcripts associated with the cardiac maturation gene program. (Created with Biorender.)
See this image and copyright information in PMC

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References

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