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Comment
. 2024 Jun;177(6):JC62.
doi: 10.7326/ANNALS-24-00210-JC. Epub 2024 Jun 4.

In septic shock and CAP, hydrocortisone + fludrocortisone reduced 90-d mortality

Dennis G Maki  1
Affiliations
Comment

In septic shock and CAP, hydrocortisone + fludrocortisone reduced 90-d mortality

Dennis G Maki. Ann Intern Med. 2024 Jun.

Abstract

Heming N, Renault A, Kuperminc E, et al; APROCCHSS investigators and CRICS-TRIGGERSEP network. Hydrocortisone plus fludrocortisone for community acquired pneumonia-related septic shock: a subgroup analysis of the APROCCHSS phase 3 randomised trial. Lancet Respir Med. 2024;12:366-374. 38310918.

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Conflict of interest statement

Disclosures: Disclosure forms are available with the article online.

Comment on

  • Hydrocortisone plus fludrocortisone for community acquired pneumonia-related septic shock: a subgroup analysis of the APROCCHSS phase 3 randomised trial.
    Heming N, Renault A, Kuperminc E, Brun-Buisson C, Megarbane B, Quenot JP, Siami S, Cariou A, Forceville X, Schwebel C, Leone M, Timsit JF, Misset B, Benali MA, Colin G, Souweine B, Asehnoune K, Mercier E, Chimot L, Charpentier C, François B, Boulain T, Petitpas F, Constantin JM, Dhonneur G, Baudin F, Combes A, Bohé J, Loriferne JF, Cook F, Slama M, Leroy O, Capellier G, Dargent A, Hissem T, Bounab R, Maxime V, Moine P, Bellissant E, Annane D; APROCCHSS investigators; CRICS-TRIGGERSEP network. Heming N, et al. Lancet Respir Med. 2024 May;12(5):366-374. doi: 10.1016/S2213-2600(23)00430-7. Epub 2024 Feb 1. Lancet Respir Med. 2024. PMID: 38310918 Clinical Trial.

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