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Review
. 2024 Aug 1;36(4):400-405.
doi: 10.1097/MOP.0000000000001370. Epub 2024 Jun 3.

Vulvar skin disease in the pediatric population

Taylor Griffith  1 , Madeline Hunt  2 , Kalyani Marathe  2   3
Affiliations
Review

Vulvar skin disease in the pediatric population

Taylor Griffith et al. Curr Opin Pediatr. .

Abstract

Purpose of review: Vulvar skin disease is an underrecognized pediatric condition encompassing a wide range of conditions, from isolated vulvar disease to vulvar manifestations of systemic illnesses. This review highlights the most current research discussing clinical features, risk factors, and treatments.

Recent findings: Recent studies confirm that labial adhesions resolve more quickly with estrogen treatment. Topical corticosteroids remain first-line for treatment of vulvar lichen sclerosus, and some procedural interventions are showing promising results. Latest evidence shows efficacy of biologic agents in hidradenitis suppurativa and vulvar Crohn's. Vaginal voiding remains an underrecognized cause of irritant vulvovaginitis. Lately vulvar aphthae have been associated with coronavirus disease 2019. Distinguishing between infantile perianal pyramidal protrusion, molluscum, and condyloma can be aided by differences in morphologic features.

Summary: Vulvar dermatoses have a high impact on children's health and wellbeing. Clinician familiarity with recognition and latest advancements in vulvar dermatoses can aid in prompt diagnosis, management, and appropriate referrals. Vulvar biopsy and vaginal cultures should be used prudently. Treatments include topicals, behavioral modification, systemic medications, and procedures.

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References

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    1. Brander EPA, McQuillan SK. Prepubertal vulvovaginitis. CMAJ 2018; 190:E800.
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    1. Kim SW, Han JY, Han SJ, et al. Effect of topical estrogen cream compared with observation in prepubertal girls with labial adhesions. J Pediatr Urol 2023; 19:403.e1–403.e6.
    1. Drever N, Peek S, Moussaoui D, et al. Vaginal bleeding in children: a retrospective audit at a tertiary paediatric gynaecology service. J Paediatr Child Health 2023; 59:653–659.