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Review
. 2024 Jul 1;27(4):338-343.
doi: 10.1097/MCO.0000000000001044. Epub 2024 Jun 6.

The impact of slowly digestible and resistant starch on glucose homeostasis and insulin resistance

Maëliss Chisbert  1 , Anne-Laure Castell  1   2 , Sophie Vinoy  3 , Julie-Anne Nazare  1
Affiliations
Review

The impact of slowly digestible and resistant starch on glucose homeostasis and insulin resistance

Maëliss Chisbert et al. Curr Opin Clin Nutr Metab Care. .

Abstract

Purpose of review: This review will summarize recent studies assessing the effect of slowly digestible starch (SDS) and resistant starch (RS) on glucose metabolism in healthy, prediabetic or type 2 diabetic adults.

Recent findings: Currently, a particular interest in starch and its digestibility has arisen, with data showing a positive effect of SDS and RS on the glucose homeostasis of healthy, at-risk, prediabetic and type 2 diabetic patients but research is ongoing.

Summary: Carbohydrates (CHO) and especially starch play a major role in the prevention and management of metabolic diseases such as type 2 diabetes (T2D). This largely depends on the quality and the digestibility (rate and extent) of the ingested starchy products, beyond their quantity. SDS have been poorly studied but display a beneficial effect on reducing glucose excursions in healthy and insulin-resistant subjects and a relevant potential to improve glucose control in type 2 diabetic individuals. As for RS, the results appear to be encouraging but remain heterogeneous, depending the nature of the RS and its role on microbiota modulation. Further studies are needed to confirm the present results and investigate the potential complementary beneficial effects of SDS and RS on long-term glucose homeostasis to prevent cardiometabolic diseases.

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Conflict of interest statement

S.V. is an employee of Mondelez International R&D.

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